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- W2053458045 abstract "ABSTRACT. A single sensillum on each galea of adult Colorado beetles contains a cell which is highly sensitive to amino acids. The cell has a marked specificity for L-alanine and γ-amino butyric acid (GABA); other amino acids tested were at least 10 times less effective as stimulants. From a structure-activity study, using compounds with longer and shorter carbon chains than GABA and longer chains than L-alanine, it is apparent that the receptor is very sensitive to minor changes in these two stimulating molecules. It is argued that the receptor evolved in a form sensitive to L-alanine, and that GABA is effective because it can bend into a configuration which mimics L-alanine in terms of important active sites for the receptor system. This specific receptor for an important class of phagostimulants provides an opportunity for future studies in comparative receptor physiology." @default.
- W2053458045 created "2016-06-24" @default.
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- W2053458045 date "1985-12-01" @default.
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- W2053458045 title "Specificity of an amino acid-sensitive cell in the adult Colorado beetle, Leptinotarsa decemlineata" @default.
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- W2053458045 doi "https://doi.org/10.1111/j.1365-3032.1985.tb00063.x" @default.
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