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- W2053485877 abstract "The effect of amphotericin B on human and murine hematopoiesis was studied in vitro using assays for erythroid and myeloid colony-forming cells. Amphotericin consistently inhibited colony formation by erythroid and granulocyte-monocyte progenitor cells. Clear effects were observable at amphotericin concentrations of 1.0 μg/ml, and concentrations of 2.0 μg/ml caused approximately 50-60% inhibition of cloning of both murine and normal human bone marrow. These data suggest that amphotericin, in concentrations achieved in therapy, can impair hematopoiesis by a direct effect on precursor cells." @default.
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- W2053485877 date "1977-01-01" @default.
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- W2053485877 title "Amphotericin inhibition of hematopoiesis in vitro" @default.
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- W2053485877 doi "https://doi.org/10.1002/ajh.2830030107" @default.
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