FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2053507339> ?p ?o ?g. }

• W2053507339 endingPage "206" @default.
• W2053507339 startingPage "189" @default.
• W2053507339 abstract "Cocaine conditioned stimuli are capable of eliciting cocaine craving in individuals with a history of cocaine use. As a consequence, there have been a number of attempts using animal models to identify pharmacological treatments which can attenuate cocaine conditioned effects. The emphasis in these studies has been to employ drug doses which do not have response effects that could directly alter the conditioned drug response. A drug treatment may not have a response effect but still have drug stimulus effects which could interact with and modify the cocaine conditioned stimulus. In order to experimentally investigate this important issue, two experiments are reported. In one experiment, rats were co-administered 0.1 mg/kg MK-801 either with cocaine (10 mg/kg) or with saline; in the other experiment 3.0 mg/kg buspirone was co-administered with either cocaine (10 mg/kg) or with saline. The MK-801 and buspirone treatments did not affect spontaneous activity levels or alter the unconditioned cocaine stimulant effect. In tests for conditioning, however, the effects of buspirone and MK-801 depended upon their association with cocaine. If MK-801 and buspirone had no association with cocaine then these drugs inactivated the cocaine conditioned stimulant response. If MK-801 and buspirone had been co-administered with cocaine, then, in saline conditioning tests, no cocaine conditioning was observed. If the conditioning tests were conducted following MK-801 or buspirone treatment, however, cocaine conditioning was elicited. Altogether, these studies demonstrate that the stimulus properties of drugs can interact with contextual stimuli to inactivate or activate cocaine conditioned stimuli. In the search for drugs which may prevent cocaine craving, therefore, the stimulus properties of drugs provide an important mechanism for the modification of cocaine conditioned stimuli." @default.
• W2053507339 created "2016-06-24" @default.
• W2053507339 creator A5031455949 @default.
• W2053507339 creator A5063895426 @default.
• W2053507339 creator A5088579403 @default.
• W2053507339 date "1999-06-01" @default.
• W2053507339 modified "2023-10-14" @default.
• W2053507339 title "Issues in the pharmacological modification of cocaine conditioning: evidence that the stimulus properties of drugs can interact with contextual cues to activate or inactivate cocaine conditioned stimuli" @default.
• W2053507339 cites W1964940552 @default.
• W2053507339 cites W1966795950 @default.
• W2053507339 cites W1967923482 @default.
• W2053507339 cites W1979017418 @default.
• W2053507339 cites W1988433095 @default.
• W2053507339 cites W1988859060 @default.
• W2053507339 cites W1991007999 @default.
• W2053507339 cites W1993308253 @default.
• W2053507339 cites W1993850362 @default.
• W2053507339 cites W1994617447 @default.
• W2053507339 cites W1999171131 @default.
• W2053507339 cites W2001865657 @default.
• W2053507339 cites W2004184263 @default.
• W2053507339 cites W2007689138 @default.
• W2053507339 cites W2009957975 @default.
• W2053507339 cites W2023230228 @default.
• W2053507339 cites W2030255787 @default.
• W2053507339 cites W2034788887 @default.
• W2053507339 cites W2036274140 @default.
• W2053507339 cites W2041182780 @default.
• W2053507339 cites W2047147502 @default.
• W2053507339 cites W2051097170 @default.
• W2053507339 cites W2051952783 @default.
• W2053507339 cites W2052205730 @default.
• W2053507339 cites W2055207238 @default.
• W2053507339 cites W2055951343 @default.
• W2053507339 cites W2061407189 @default.
• W2053507339 cites W2063183398 @default.
• W2053507339 cites W2070765568 @default.
• W2053507339 cites W2075396924 @default.
• W2053507339 cites W2079275626 @default.
• W2053507339 cites W2083742222 @default.
• W2053507339 cites W2085492436 @default.
• W2053507339 cites W2086087006 @default.
• W2053507339 cites W2087685262 @default.
• W2053507339 cites W2093052238 @default.
• W2053507339 cites W2099654640 @default.
• W2053507339 cites W2104601786 @default.
• W2053507339 cites W2111560916 @default.
• W2053507339 cites W2125697983 @default.
• W2053507339 cites W2163324649 @default.
• W2053507339 cites W2255361692 @default.
• W2053507339 cites W4230983096 @default.
• W2053507339 doi "https://doi.org/10.1016/s0166-4328(98)00149-1" @default.
• W2053507339 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10372574" @default.
• W2053507339 hasPublicationYear "1999" @default.
• W2053507339 type Work @default.
• W2053507339 sameAs 2053507339 @default.
• W2053507339 citedByCount "13" @default.
• W2053507339 countsByYear W20535073392012 @default.
• W2053507339 countsByYear W20535073392015 @default.
• W2053507339 countsByYear W20535073392017 @default.
• W2053507339 crossrefType "journal-article" @default.
• W2053507339 hasAuthorship W2053507339A5031455949 @default.
• W2053507339 hasAuthorship W2053507339A5063895426 @default.
• W2053507339 hasAuthorship W2053507339A5088579403 @default.
• W2053507339 hasConcept C105795698 @default.
• W2053507339 hasConcept C118552586 @default.
• W2053507339 hasConcept C126322002 @default.
• W2053507339 hasConcept C15744967 @default.
• W2053507339 hasConcept C169760540 @default.
• W2053507339 hasConcept C170493617 @default.
• W2053507339 hasConcept C180747234 @default.
• W2053507339 hasConcept C2777287423 @default.
• W2053507339 hasConcept C2778938600 @default.
• W2053507339 hasConcept C2779547902 @default.
• W2053507339 hasConcept C2779918689 @default.
• W2053507339 hasConcept C2780557958 @default.
• W2053507339 hasConcept C33923547 @default.
• W2053507339 hasConcept C35124327 @default.
• W2053507339 hasConcept C39617858 @default.
• W2053507339 hasConcept C45262634 @default.
• W2053507339 hasConcept C48856860 @default.
• W2053507339 hasConcept C57022672 @default.
• W2053507339 hasConcept C71924100 @default.
• W2053507339 hasConcept C98274493 @default.
• W2053507339 hasConceptScore W2053507339C105795698 @default.
• W2053507339 hasConceptScore W2053507339C118552586 @default.
• W2053507339 hasConceptScore W2053507339C126322002 @default.
• W2053507339 hasConceptScore W2053507339C15744967 @default.
• W2053507339 hasConceptScore W2053507339C169760540 @default.
• W2053507339 hasConceptScore W2053507339C170493617 @default.
• W2053507339 hasConceptScore W2053507339C180747234 @default.
• W2053507339 hasConceptScore W2053507339C2777287423 @default.
• W2053507339 hasConceptScore W2053507339C2778938600 @default.
• W2053507339 hasConceptScore W2053507339C2779547902 @default.
• W2053507339 hasConceptScore W2053507339C2779918689 @default.
• W2053507339 hasConceptScore W2053507339C2780557958 @default.
• W2053507339 hasConceptScore W2053507339C33923547 @default.
• W2053507339 hasConceptScore W2053507339C35124327 @default.

• next