FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2053546660> ?p ?o ?g. }

• W2053546660 endingPage "1080" @default.
• W2053546660 startingPage "1076" @default.
• W2053546660 abstract "The systemic inflammatory response, as evidenced by elevated circulating concentrations of C-reactive protein, is a stage-independent prognostic factor in patients undergoing curative nephrectomy for localised renal cancer. However, it is not clear whether the systemic inflammatory response arises from the tumour per se or as a result of an impaired immune cytokine response. The aim of the present study was to examine C-reactive protein, interleukin-6 and interleukin-10 concentrations before and following curative resection of renal cancer. Sixty-four patients with malignant renal disease and 12 with benign disease, undergoing resection were studied. Preoperatively, a blood sample was collected for routine laboratory analysis with a further sample stored before analysis of interleukin-6 and interleukin-10 using an enzyme-linked immunosorbent assay (ELISA) technique. The blood sampling procedure and analyses were repeated at approximately 3 months following resection. Circulating concentrations of both interleukin-6 and interleukin (P⩽0.01) were higher and a greater proportion were elevated (P<0.05) in malignant compared with benign disease. The renal cancer patients were grouped according to whether they had evidence of a systemic inflammatory response. In the inflammatory group T stage was higher (P<0.01), both interleukin-6 and interleukin-10 concentrations were higher (P<0.001) and elevated (P<0.10) compared with the non-inflammatory group. Tumour volume was weakly correlated with C-reactive protein (r2=0.20, P=0.002), interleukin-6 (r2=0.20, P=0.002) and interleukin-10 (r2=0.24, P=0.001). Following nephrectomy the proportion of patients with elevated C-reactive protein, interleukin-6 and interleukin-10 concentrations did not alter significantly. An elevated preoperative C-reactive protein was associated with increased tumour stage, interleukin-6 and interleukin-10 concentrations. However, resection of the primary tumour did not appear to be associated with significant normalisation of circulating concentrations of C-reactive protein, interleukin-6 or interleukin-10. Therefore, the presence of systemic inflammatory response is unlikely to be solely be determined by the tumour itself, but may be as a result of an impaired immune cytokine response in patients with renal cancer." @default.
• W2053546660 created "2016-06-24" @default.
• W2053546660 creator A5047957075 @default.
• W2053546660 creator A5084664528 @default.
• W2053546660 creator A5085683838 @default.
• W2053546660 creator A5086554206 @default.
• W2053546660 date "2006-09-26" @default.
• W2053546660 modified "2023-10-09" @default.
• W2053546660 title "The longitudinal relationship between circulating concentrations of C-reactive protein, interleukin-6 and interleukin-10 in patients undergoing resection for renal cancer" @default.
• W2053546660 cites W1964795510 @default.
• W2053546660 cites W1966763590 @default.
• W2053546660 cites W1967836453 @default.
• W2053546660 cites W1985354647 @default.
• W2053546660 cites W1987417042 @default.
• W2053546660 cites W1987755269 @default.
• W2053546660 cites W1991258536 @default.
• W2053546660 cites W1993133962 @default.
• W2053546660 cites W2011532948 @default.
• W2053546660 cites W2017375854 @default.
• W2053546660 cites W2033518882 @default.
• W2053546660 cites W2034681353 @default.
• W2053546660 cites W2039545078 @default.
• W2053546660 cites W2074243608 @default.
• W2053546660 cites W2078878717 @default.
• W2053546660 cites W2091974678 @default.
• W2053546660 cites W2111675032 @default.
• W2053546660 cites W2113874226 @default.
• W2053546660 cites W2130290528 @default.
• W2053546660 cites W2317184793 @default.
• W2053546660 cites W2408098338 @default.
• W2053546660 doi "https://doi.org/10.1038/sj.bjc.6603387" @default.
• W2053546660 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2360708" @default.
• W2053546660 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17003778" @default.
• W2053546660 hasPublicationYear "2006" @default.
• W2053546660 type Work @default.
• W2053546660 sameAs 2053546660 @default.
• W2053546660 citedByCount "39" @default.
• W2053546660 countsByYear W20535466602012 @default.
• W2053546660 countsByYear W20535466602013 @default.
• W2053546660 countsByYear W20535466602014 @default.
• W2053546660 countsByYear W20535466602015 @default.
• W2053546660 countsByYear W20535466602016 @default.
• W2053546660 countsByYear W20535466602017 @default.
• W2053546660 countsByYear W20535466602018 @default.
• W2053546660 countsByYear W20535466602019 @default.
• W2053546660 countsByYear W20535466602020 @default.
• W2053546660 countsByYear W20535466602021 @default.
• W2053546660 countsByYear W20535466602022 @default.
• W2053546660 crossrefType "journal-article" @default.
• W2053546660 hasAuthorship W2053546660A5047957075 @default.
• W2053546660 hasAuthorship W2053546660A5084664528 @default.
• W2053546660 hasAuthorship W2053546660A5085683838 @default.
• W2053546660 hasAuthorship W2053546660A5086554206 @default.
• W2053546660 hasBestOaLocation W20535466601 @default.
• W2053546660 hasConcept C11988809 @default.
• W2053546660 hasConcept C121608353 @default.
• W2053546660 hasConcept C126322002 @default.
• W2053546660 hasConcept C2776914184 @default.
• W2053546660 hasConcept C2777371288 @default.
• W2053546660 hasConcept C2778690821 @default.
• W2053546660 hasConcept C2780091579 @default.
• W2053546660 hasConcept C2780227381 @default.
• W2053546660 hasConcept C2781195455 @default.
• W2053546660 hasConcept C71924100 @default.
• W2053546660 hasConcept C74172505 @default.
• W2053546660 hasConcept C90924648 @default.
• W2053546660 hasConceptScore W2053546660C11988809 @default.
• W2053546660 hasConceptScore W2053546660C121608353 @default.
• W2053546660 hasConceptScore W2053546660C126322002 @default.
• W2053546660 hasConceptScore W2053546660C2776914184 @default.
• W2053546660 hasConceptScore W2053546660C2777371288 @default.
• W2053546660 hasConceptScore W2053546660C2778690821 @default.
• W2053546660 hasConceptScore W2053546660C2780091579 @default.
• W2053546660 hasConceptScore W2053546660C2780227381 @default.
• W2053546660 hasConceptScore W2053546660C2781195455 @default.
• W2053546660 hasConceptScore W2053546660C71924100 @default.
• W2053546660 hasConceptScore W2053546660C74172505 @default.
• W2053546660 hasConceptScore W2053546660C90924648 @default.
• W2053546660 hasIssue "8" @default.
• W2053546660 hasLocation W20535466601 @default.
• W2053546660 hasLocation W20535466602 @default.
• W2053546660 hasLocation W20535466603 @default.
• W2053546660 hasLocation W20535466604 @default.
• W2053546660 hasOpenAccess W2053546660 @default.
• W2053546660 hasPrimaryLocation W20535466601 @default.
• W2053546660 hasRelatedWork W1962212603 @default.
• W2053546660 hasRelatedWork W1965279128 @default.
• W2053546660 hasRelatedWork W1981857027 @default.
• W2053546660 hasRelatedWork W1998739014 @default.
• W2053546660 hasRelatedWork W2018117734 @default.
• W2053546660 hasRelatedWork W2035145483 @default.
• W2053546660 hasRelatedWork W2076481434 @default.
• W2053546660 hasRelatedWork W2097636587 @default.
• W2053546660 hasRelatedWork W2359429840 @default.
• W2053546660 hasRelatedWork W4300173484 @default.
• W2053546660 hasVolume "95" @default.
• W2053546660 isParatext "false" @default.
• W2053546660 isRetracted "false" @default.

• next