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• W2053550842 abstract "Legionnaires’ disease is the pneumonia produced by Legionella pneumophila, a newly recognized gram-negative bacillus. 1 Fraser DW Tsai (sic), TR Orenstein W Parkin WE Beecham HJ Sharrar RG et al. Legionnaires’ disease: description of an epidemic of pneumonia. N Engl J Med. 1977; 297: 1189-1197 Crossref PubMed Scopus (1281) Google Scholar , 2 McDade JE Shepard CC Fraser DW Tsai (sic), TR Redus MA Dowdle WR et al. Legionnaires’ disease: isolation of a bacterium and demonstration of its role in other respiratory disease. N Engl J Med. 1977; 297: 1197-1203 Crossref PubMed Scopus (886) Google Scholar Neither the disease nor the organism is new, as the first recorded isolation of the bacterium was in 1947, 3 Balows A Fraser DW International symposium on Legionnaires’ disease. Ann Intern Med. 1979; 90: 489-703 PubMed Google Scholar and the first well-documented outbreak of the disease occurred in 1957. 4 Osterholm MT Chin TY Osborne DO Dull HB Deon AG Fraser DW et al. A 1957 outbreak of Legionnaires’ disease associated with a meat packing plant. Am J Epidemiol. 1983; 117: 60-67 PubMed Google Scholar It was not recognized as a distinct entity until 1976, when an outbreak of pneumonia occurred among American Legionnaires in convention. 1 Fraser DW Tsai (sic), TR Orenstein W Parkin WE Beecham HJ Sharrar RG et al. Legionnaires’ disease: description of an epidemic of pneumonia. N Engl J Med. 1977; 297: 1189-1197 Crossref PubMed Scopus (1281) Google Scholar Subsequent to recognition of the disease and rediscovery of the organism, many thousands of cases of this disease have been diagnosed worldwide. A nonpneumonic form of disease associated with L pneumophila (Pontiac fever) has been described, and at least nine other species have been discovered or rediscovered. 5 Lattimer GL Ormsbee RA Legionnaires’ disease. Marcel Dekker, Inc, New York1981 Google Scholar , 6 Meyer RD Legionella infections: a review of five years of research. Rev Infect Dis. 1983; 5: 258-278 Crossref PubMed Scopus (91) Google Scholar This review will focus primarily on pneumonia due to L pneumophila, mainly because relatively little is known about infection caused by the other species. To conserve space, citations of literature will frequently be to reviews, rather than primary publications." @default.
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• W2053550842 date "1984-01-01" @default.
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• W2053550842 title "Legionnaires’ Disease" @default.
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