FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2053600540> ?p ?o ?g. }

• W2053600540 endingPage "1114" @default.
• W2053600540 startingPage "1107" @default.
• W2053600540 abstract "This study was aimed to evaluate the source of endothelin-1 (ET-1) in cirrhotic patients. ET-1 is implicated in the pathogenesis of portal hypertension. However, the mechanism and source for increased plasma ET-1 in cirrhotic patients are still obscure. Plasma ET-1 levels in systemic (SV), superior mesenteric (SMV), and splenic venous (SPV) blood were measured in 23 patients with cirrhosis and 8 controls with normal liver. Fourteen removed spleens were immunohistochemically studied for ET-1, CD34, CD68, and CD20. In situ hybridization was done to localize ET-1 messenger RNA (mRNA). In cirrhosis, ET-1 levels in both SMV and SPV were higher than in SV. ET-1 in SV and SPV were significantly higher in cirrhotic patients than in control patients. Three groups of cells in the spleen expressed both protein and mRNA of ET-1: endothelial cells in the sinus, which were also stained for CD34; cells in the germinal center; and cells in the marginal zone of lymphoid sheaths and follicles, which were also stained for CD20 but not for CD34 and CD68. The ET-1 concentration released from the spleen was in parallel with the grade of ET-1 expression in the spleen. The spleen is one of the major sites of ET-1 release in cirrhotic patients. Endothelial cells of the splenic sinus and possibly B lymphocytes in the germinal center and marginal zone of lymphoid sheaths and follicles seem to be the sites of ET-1 production in the spleen." @default.
• W2053600540 created "2016-06-24" @default.
• W2053600540 creator A5002085584 @default.
• W2053600540 creator A5002791969 @default.
• W2053600540 creator A5030048967 @default.
• W2053600540 creator A5042986871 @default.
• W2053600540 creator A5048027547 @default.
• W2053600540 creator A5062486824 @default.
• W2053600540 creator A5062704912 @default.
• W2053600540 creator A5063964608 @default.
• W2053600540 creator A5070926530 @default.
• W2053600540 creator A5078368687 @default.
• W2053600540 date "2000-05-01" @default.
• W2053600540 modified "2023-10-06" @default.
• W2053600540 title "production and release of endothelin-1 from the gut and spleen in portal hypertension due to cirrhosis" @default.
• W2053600540 cites W1267147680 @default.
• W2053600540 cites W1513510460 @default.
• W2053600540 cites W1537279861 @default.
• W2053600540 cites W1894472884 @default.
• W2053600540 cites W1964217931 @default.
• W2053600540 cites W1973278518 @default.
• W2053600540 cites W1977983569 @default.
• W2053600540 cites W1980762198 @default.
• W2053600540 cites W1985403454 @default.
• W2053600540 cites W1991236355 @default.
• W2053600540 cites W1997145129 @default.
• W2053600540 cites W1999509812 @default.
• W2053600540 cites W2007575271 @default.
• W2053600540 cites W2015050659 @default.
• W2053600540 cites W2017054020 @default.
• W2053600540 cites W2018806392 @default.
• W2053600540 cites W2026052900 @default.
• W2053600540 cites W2026464043 @default.
• W2053600540 cites W2041553454 @default.
• W2053600540 cites W2043296219 @default.
• W2053600540 cites W2052814004 @default.
• W2053600540 cites W2059369537 @default.
• W2053600540 cites W2063576679 @default.
• W2053600540 cites W2070913408 @default.
• W2053600540 cites W2075907485 @default.
• W2053600540 cites W2095571216 @default.
• W2053600540 cites W2111651135 @default.
• W2053600540 cites W2121591560 @default.
• W2053600540 cites W2124334318 @default.
• W2053600540 cites W2151869895 @default.
• W2053600540 cites W2154640429 @default.
• W2053600540 cites W2156807957 @default.
• W2053600540 cites W2162804111 @default.
• W2053600540 cites W2169058381 @default.
• W2053600540 cites W2170155226 @default.
• W2053600540 cites W2414350339 @default.
• W2053600540 cites W2415183088 @default.
• W2053600540 cites W4244089942 @default.
• W2053600540 cites W4246914844 @default.
• W2053600540 doi "https://doi.org/10.1053/he.2000.6596" @default.
• W2053600540 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10796886" @default.
• W2053600540 hasPublicationYear "2000" @default.
• W2053600540 type Work @default.
• W2053600540 sameAs 2053600540 @default.
• W2053600540 citedByCount "63" @default.
• W2053600540 countsByYear W20536005402012 @default.
• W2053600540 countsByYear W20536005402013 @default.
• W2053600540 countsByYear W20536005402014 @default.
• W2053600540 countsByYear W20536005402016 @default.
• W2053600540 countsByYear W20536005402017 @default.
• W2053600540 countsByYear W20536005402018 @default.
• W2053600540 countsByYear W20536005402020 @default.
• W2053600540 countsByYear W20536005402021 @default.
• W2053600540 countsByYear W20536005402022 @default.
• W2053600540 countsByYear W20536005402023 @default.
• W2053600540 crossrefType "journal-article" @default.
• W2053600540 hasAuthorship W2053600540A5002085584 @default.
• W2053600540 hasAuthorship W2053600540A5002791969 @default.
• W2053600540 hasAuthorship W2053600540A5030048967 @default.
• W2053600540 hasAuthorship W2053600540A5042986871 @default.
• W2053600540 hasAuthorship W2053600540A5048027547 @default.
• W2053600540 hasAuthorship W2053600540A5062486824 @default.
• W2053600540 hasAuthorship W2053600540A5062704912 @default.
• W2053600540 hasAuthorship W2053600540A5063964608 @default.
• W2053600540 hasAuthorship W2053600540A5070926530 @default.
• W2053600540 hasAuthorship W2053600540A5078368687 @default.
• W2053600540 hasBestOaLocation W20536005401 @default.
• W2053600540 hasConcept C10205521 @default.
• W2053600540 hasConcept C104317684 @default.
• W2053600540 hasConcept C105580179 @default.
• W2053600540 hasConcept C126322002 @default.
• W2053600540 hasConcept C134018914 @default.
• W2053600540 hasConcept C142724271 @default.
• W2053600540 hasConcept C159654299 @default.
• W2053600540 hasConcept C203014093 @default.
• W2053600540 hasConcept C204232928 @default.
• W2053600540 hasConcept C2776460901 @default.
• W2053600540 hasConcept C2777214474 @default.
• W2053600540 hasConcept C2778453870 @default.
• W2053600540 hasConcept C2778808290 @default.
• W2053600540 hasConcept C2780931953 @default.
• W2053600540 hasConcept C28328180 @default.
• W2053600540 hasConcept C54355233 @default.

• next