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- W2053614552 abstract "A case of pulmonary hypertension (PAH) secondary to fibrosing alveolitis is described. PAH can occur for three essential reasons i) increased volume of pulmonary blood flow ii) enhanced pulmonary vascular resistance and iii) elevations in pulmonary venous pressure. Important mediators of pulmonary arterial tone include nitric oxide (NO), prostacyclin, endothelin-1 and phosphodiesterase 5 (PDE 5) activity. The goals of treatment in states of pulmonary hypertension are to promote vasorelaxation, suppress cellular proliferation, induce apoptosis within the pulmonary arterial wall and improve right ventricular function. Treatment options include sildenafil and pimobendan. In this case both drugs were used but benefit was short-lived." @default.
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- W2053614552 date "2011-06-01" @default.
- W2053614552 modified "2023-09-25" @default.
- W2053614552 title "Fibrosing alveolitis and pulmonary arterial hypertension in a West Highland White Terrier" @default.
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- W2053614552 doi "https://doi.org/10.1111/j.2044-3862.2011.00059.x" @default.
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