Matches in SemOpenAlex for { <https://semopenalex.org/work/W2053623445> ?p ?o ?g. }
- W2053623445 endingPage "2506" @default.
- W2053623445 startingPage "2500" @default.
- W2053623445 abstract "NELL1 is a secretory osteogenic protein containing several structural motifs that suggest that it functions as an extracellular matrix component. To determine the mechanisms underlying NELL1-induced osteoblast differentiation, we examined the cell-adhesive activity of NELL1 using a series of recombinant NELL1 proteins. We demonstrated that NELL1 promoted osteoblastic cell adhesion through at least three cell-binding domains located in the C-terminal region of NELL1. Adhesion of cells to NELL1 was strongly inhibited by function-blocking antibodies against integrin α3 and β1 subunits, suggesting that osteoblastic cells adhered to NELL1 through integrin α3β1. Further, focal adhesion kinase activation is involved in NELL1 signaling." @default.
- W2053623445 created "2016-06-24" @default.
- W2053623445 creator A5008580304 @default.
- W2053623445 creator A5029907365 @default.
- W2053623445 creator A5032237331 @default.
- W2053623445 creator A5035549362 @default.
- W2053623445 creator A5040243865 @default.
- W2053623445 creator A5062987455 @default.
- W2053623445 creator A5065624582 @default.
- W2053623445 creator A5083631522 @default.
- W2053623445 creator A5084295127 @default.
- W2053623445 date "2012-06-20" @default.
- W2053623445 modified "2023-10-13" @default.
- W2053623445 title "The C-terminal region of NELL1 mediates osteoblastic cell adhesion through integrin α3β1" @default.
- W2053623445 cites W1988502218 @default.
- W2053623445 cites W1993757797 @default.
- W2053623445 cites W2006056970 @default.
- W2053623445 cites W2015292055 @default.
- W2053623445 cites W2022407580 @default.
- W2053623445 cites W2031066958 @default.
- W2053623445 cites W2035375968 @default.
- W2053623445 cites W2041287210 @default.
- W2053623445 cites W2055584330 @default.
- W2053623445 cites W2056886043 @default.
- W2053623445 cites W2060830074 @default.
- W2053623445 cites W2061323485 @default.
- W2053623445 cites W2065940152 @default.
- W2053623445 cites W2083544543 @default.
- W2053623445 cites W2085777866 @default.
- W2053623445 cites W2089360761 @default.
- W2053623445 cites W2114413533 @default.
- W2053623445 cites W2114874277 @default.
- W2053623445 cites W2117006539 @default.
- W2053623445 cites W2129611079 @default.
- W2053623445 cites W2132620372 @default.
- W2053623445 cites W2133607414 @default.
- W2053623445 cites W2149193631 @default.
- W2053623445 cites W2160638201 @default.
- W2053623445 cites W2160870063 @default.
- W2053623445 cites W2168918180 @default.
- W2053623445 cites W2169318446 @default.
- W2053623445 cites W27153472 @default.
- W2053623445 cites W2944147705 @default.
- W2053623445 cites W4213141530 @default.
- W2053623445 doi "https://doi.org/10.1016/j.febslet.2012.06.014" @default.
- W2053623445 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22728432" @default.
- W2053623445 hasPublicationYear "2012" @default.
- W2053623445 type Work @default.
- W2053623445 sameAs 2053623445 @default.
- W2053623445 citedByCount "23" @default.
- W2053623445 countsByYear W20536234452013 @default.
- W2053623445 countsByYear W20536234452014 @default.
- W2053623445 countsByYear W20536234452015 @default.
- W2053623445 countsByYear W20536234452017 @default.
- W2053623445 countsByYear W20536234452018 @default.
- W2053623445 countsByYear W20536234452019 @default.
- W2053623445 countsByYear W20536234452020 @default.
- W2053623445 countsByYear W20536234452021 @default.
- W2053623445 countsByYear W20536234452022 @default.
- W2053623445 countsByYear W20536234452023 @default.
- W2053623445 crossrefType "journal-article" @default.
- W2053623445 hasAuthorship W2053623445A5008580304 @default.
- W2053623445 hasAuthorship W2053623445A5029907365 @default.
- W2053623445 hasAuthorship W2053623445A5032237331 @default.
- W2053623445 hasAuthorship W2053623445A5035549362 @default.
- W2053623445 hasAuthorship W2053623445A5040243865 @default.
- W2053623445 hasAuthorship W2053623445A5062987455 @default.
- W2053623445 hasAuthorship W2053623445A5065624582 @default.
- W2053623445 hasAuthorship W2053623445A5083631522 @default.
- W2053623445 hasAuthorship W2053623445A5084295127 @default.
- W2053623445 hasBestOaLocation W20536234451 @default.
- W2053623445 hasConcept C1491633281 @default.
- W2053623445 hasConcept C151166631 @default.
- W2053623445 hasConcept C156585808 @default.
- W2053623445 hasConcept C16224149 @default.
- W2053623445 hasConcept C185592680 @default.
- W2053623445 hasConcept C189165786 @default.
- W2053623445 hasConcept C195687474 @default.
- W2053623445 hasConcept C4894155 @default.
- W2053623445 hasConcept C55493867 @default.
- W2053623445 hasConcept C62478195 @default.
- W2053623445 hasConcept C85789140 @default.
- W2053623445 hasConcept C86803240 @default.
- W2053623445 hasConcept C95444343 @default.
- W2053623445 hasConceptScore W2053623445C1491633281 @default.
- W2053623445 hasConceptScore W2053623445C151166631 @default.
- W2053623445 hasConceptScore W2053623445C156585808 @default.
- W2053623445 hasConceptScore W2053623445C16224149 @default.
- W2053623445 hasConceptScore W2053623445C185592680 @default.
- W2053623445 hasConceptScore W2053623445C189165786 @default.
- W2053623445 hasConceptScore W2053623445C195687474 @default.
- W2053623445 hasConceptScore W2053623445C4894155 @default.
- W2053623445 hasConceptScore W2053623445C55493867 @default.
- W2053623445 hasConceptScore W2053623445C62478195 @default.
- W2053623445 hasConceptScore W2053623445C85789140 @default.
- W2053623445 hasConceptScore W2053623445C86803240 @default.
- W2053623445 hasConceptScore W2053623445C95444343 @default.
- W2053623445 hasIssue "16" @default.