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- W2053641844 abstract "We evaluated the efficacy and safety of alteplase to restore central venous line (CVL) patency in a consecutive cohort study. A uniform, weight-dependent protocol for alteplase administration was established prospectively. For children < or =10 kg, a dose of 0.5 mg was used; for children >10 kg, doses of 1 to 2 mg were used. The alteplase remained instilled for 1 to 4 hours or overnight. Retrospective data accrual found that 25 children received alteplase for a total of 34 courses; 29 (85%) of the 34 courses of alteplase completely restored CVL patency. Alteplase appears to be a safe and effective thrombolytic agent for CVL patency restoration in children." @default.
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- W2053641844 date "2001-07-01" @default.
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- W2053641844 title "The use of alteplase to restore patency of central venous lines in pediatric patients: A cohort study" @default.
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- W2053641844 doi "https://doi.org/10.1067/mpd.2001.115019" @default.
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