FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2053657148> ?p ?o ?g. }

• W2053657148 endingPage "204" @default.
• W2053657148 startingPage "199" @default.
• W2053657148 abstract "Background Breast conserving surgery (BCS) is increasingly offered to suitable patients diagnosed with early stage breast cancer. Occasionally the pathological margins on specimens following BCS are positive. The objective of this study is to assess the proportion of patients within our unit who required completion mastectomy after BCS and to determine if predictive factors could be identified to assist the breast surgeon identifying those patients at risk of positive margins following BCS. Methods All patients diagnosed with breast cancer between 2001 and 2005 were reviewed. Patients undergoing BCS had their histopathological specimens examined for any evidence of residual tumour at the margins of the resected specimen. These patients then proceeded to completion mastectomy if these margins were positive for residual tumour. Multinominal logistic regression was then performed on clinico-pathological factors for each of these patients to determine if predictive factors existed for determination of residual disease in the mastectomy specimen following BCS. Results Logistic regression demonstrated that size of the initial tumour was the only significant predictor for the presence of completion mastectomy residual carcinoma (CMRC) (p=0.014) and that tumours with an initial size>2.5cm were 15 times more likely to have a CMRC than tumours <1.5cm. This prediction model based on the initial tumour size had an 89.5% specificity and 52.2% sensitivity. The odds ratio for CMRC based on histological tumour type for each additional 1cm increase in size of the initial tumour was 2.82 for ductal carcinoma in situ, 2.60 for infiltrating ductal carcinoma and 2.26 for other tumours. Conclusion This study demonstrates that residual disease in total mastectomy specimens following BCS increases significantly with increasing original tumour size. With current data, surgeons can inform patients of the risks of residual cancer associated with BCS with a view to increase the rate of primary mastectomies in those patients with presenting tumours greater than 2.5cm." @default.
• W2053657148 created "2016-06-24" @default.
• W2053657148 creator A5003678491 @default.
• W2053657148 creator A5017226656 @default.
• W2053657148 creator A5026231066 @default.
• W2053657148 creator A5035217060 @default.
• W2053657148 creator A5044300869 @default.
• W2053657148 creator A5056362143 @default.
• W2053657148 date "2008-04-01" @default.
• W2053657148 modified "2023-10-17" @default.
• W2053657148 title "Completion mastectomy after breast conserving surgery" @default.
• W2053657148 cites W1946933713 @default.
• W2053657148 cites W1973478576 @default.
• W2053657148 cites W1974149616 @default.
• W2053657148 cites W1975780219 @default.
• W2053657148 cites W1976841647 @default.
• W2053657148 cites W1992369775 @default.
• W2053657148 cites W2000656440 @default.
• W2053657148 cites W2004986148 @default.
• W2053657148 cites W2026981776 @default.
• W2053657148 cites W2033660809 @default.
• W2053657148 cites W2034743672 @default.
• W2053657148 cites W2053586447 @default.
• W2053657148 cites W2060414046 @default.
• W2053657148 cites W2066741485 @default.
• W2053657148 cites W2067420088 @default.
• W2053657148 cites W2069617138 @default.
• W2053657148 cites W2070202176 @default.
• W2053657148 cites W2070665331 @default.
• W2053657148 cites W2082519986 @default.
• W2053657148 cites W2089504583 @default.
• W2053657148 cites W2105366672 @default.
• W2053657148 cites W2128153734 @default.
• W2053657148 cites W2130746306 @default.
• W2053657148 cites W2132983407 @default.
• W2053657148 cites W2158996150 @default.
• W2053657148 cites W2168124422 @default.
• W2053657148 cites W2172480593 @default.
• W2053657148 cites W2398438098 @default.
• W2053657148 cites W4293107555 @default.
• W2053657148 cites W93433362 @default.
• W2053657148 cites W1968686518 @default.
• W2053657148 doi "https://doi.org/10.1016/j.breast.2007.10.001" @default.
• W2053657148 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18024117" @default.
• W2053657148 hasPublicationYear "2008" @default.
• W2053657148 type Work @default.
• W2053657148 sameAs 2053657148 @default.
• W2053657148 citedByCount "9" @default.
• W2053657148 countsByYear W20536571482013 @default.
• W2053657148 countsByYear W20536571482014 @default.
• W2053657148 countsByYear W20536571482015 @default.
• W2053657148 countsByYear W20536571482017 @default.
• W2053657148 countsByYear W20536571482018 @default.
• W2053657148 countsByYear W20536571482021 @default.
• W2053657148 crossrefType "journal-article" @default.
• W2053657148 hasAuthorship W2053657148A5003678491 @default.
• W2053657148 hasAuthorship W2053657148A5017226656 @default.
• W2053657148 hasAuthorship W2053657148A5026231066 @default.
• W2053657148 hasAuthorship W2053657148A5035217060 @default.
• W2053657148 hasAuthorship W2053657148A5044300869 @default.
• W2053657148 hasAuthorship W2053657148A5056362143 @default.
• W2053657148 hasBestOaLocation W20536571481 @default.
• W2053657148 hasConcept C121608353 @default.
• W2053657148 hasConcept C126322002 @default.
• W2053657148 hasConcept C126838900 @default.
• W2053657148 hasConcept C141071460 @default.
• W2053657148 hasConcept C143998085 @default.
• W2053657148 hasConcept C146357865 @default.
• W2053657148 hasConcept C151730666 @default.
• W2053657148 hasConcept C151956035 @default.
• W2053657148 hasConcept C207886595 @default.
• W2053657148 hasConcept C2777546739 @default.
• W2053657148 hasConcept C2777757722 @default.
• W2053657148 hasConcept C2780862961 @default.
• W2053657148 hasConcept C2781467025 @default.
• W2053657148 hasConcept C530470458 @default.
• W2053657148 hasConcept C71924100 @default.
• W2053657148 hasConcept C86803240 @default.
• W2053657148 hasConceptScore W2053657148C121608353 @default.
• W2053657148 hasConceptScore W2053657148C126322002 @default.
• W2053657148 hasConceptScore W2053657148C126838900 @default.
• W2053657148 hasConceptScore W2053657148C141071460 @default.
• W2053657148 hasConceptScore W2053657148C143998085 @default.
• W2053657148 hasConceptScore W2053657148C146357865 @default.
• W2053657148 hasConceptScore W2053657148C151730666 @default.
• W2053657148 hasConceptScore W2053657148C151956035 @default.
• W2053657148 hasConceptScore W2053657148C207886595 @default.
• W2053657148 hasConceptScore W2053657148C2777546739 @default.
• W2053657148 hasConceptScore W2053657148C2777757722 @default.
• W2053657148 hasConceptScore W2053657148C2780862961 @default.
• W2053657148 hasConceptScore W2053657148C2781467025 @default.
• W2053657148 hasConceptScore W2053657148C530470458 @default.
• W2053657148 hasConceptScore W2053657148C71924100 @default.
• W2053657148 hasConceptScore W2053657148C86803240 @default.
• W2053657148 hasIssue "2" @default.
• W2053657148 hasLocation W20536571481 @default.
• W2053657148 hasLocation W20536571482 @default.
• W2053657148 hasOpenAccess W2053657148 @default.

• next