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• W2053662751 abstract "The signature sequence amplification method (SSAM) described herein is an approach for amplifying noncoding RNA (ncRNA), microRNA (miRNA), and small polynucleotide sequences. A key point of the SSAM technology is the generation of signature sequences. The signature sequences include target sequences (miRNA, ncRNA, and/or any small polynucleotide sequence) flanked by two DNA fragments. Target sequences can be amplified through DNA synthesis, RNA synthesis, or the combination of DNA and RNA synthesis. The amplification of signature sequences provides an efficient and reproducible mechanism to determine the presence or absence of the target miRNAs/ncRNAs, to analyze the quantities of the miRNAs in biological samples, and for miRNA/ncRNA profiling." @default.
• W2053662751 created "2016-06-24" @default.
• W2053662751 creator A5020332579 @default.
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• W2053662751 date "2014-10-24" @default.
• W2053662751 modified "2023-09-25" @default.
• W2053662751 title "Methods and Compositions for Amplification and Detection of microRNAs (miRNAs) and Noncoding RNAs (ncRNAs) Using the Signature Sequence Amplification Method (SSAM)" @default.
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• W2053662751 doi "https://doi.org/10.2174/2352092208666141001154206" @default.
• W2053662751 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4321964" @default.
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