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- W2053670331 abstract "Interest and studies focused on the role of immune and inflammatory mechanisms in vascular disease have advanced in synchrony with the advances in the understanding of innate immune system regulation and the interplay between innate and adaptive immunity. Clinical studies have implicated immune and inflammatory mechanisms in stroke and acute coronary syndromes. Analyses of genetically modified mice and in vitro and in vivo preclinical ischemia models have yielded insights into pathobiological mechanisms. Deciphering the role of innate immune mechanisms that confer tolerance to ischemia might guide translation of more effective therapies. Antigen-targeted and other forms of focused immunomodulation that can suppress vessel activation and protect ischemic tissue might ultimately find a niche in the prevention and treatment of vascular disease." @default.
- W2053670331 created "2016-06-24" @default.
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- W2053670331 creator A5017463095 @default.
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- W2053670331 date "2005-10-01" @default.
- W2053670331 modified "2023-10-17" @default.
- W2053670331 title "Immunology of ischemic vascular disease: plaque to attack" @default.
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- W2053670331 doi "https://doi.org/10.1016/j.it.2005.08.007" @default.
- W2053670331 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16109503" @default.
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