Matches in SemOpenAlex for { <https://semopenalex.org/work/W2053671128> ?p ?o ?g. }
- W2053671128 endingPage "473" @default.
- W2053671128 startingPage "464" @default.
- W2053671128 abstract "Krüppel-like factor 7 (KLF7) belongs to the large family of KLF transcription factors, which comprises at least 17 members. Within this family, KLF7 is unique since its expression is strictly restricted within the nervous system during development. We have previously shown that KLF7 is required for neuronal morphogenesis and axon guidance in selected regions of the nervous system, including hippocampus, olfactory bulbs and cortex, as well as in neuronal cell cultures. In the present work, we have furthered our analysis of the role of KLF7 in central nervous system development. By gene expression analysis during brain embryogenesis, we found significant alterations in dopaminergic neurons in Klf7 null mice. In particular, the tyrosine hydroxylase (TH) and dopamine transporter (Dat) transcripts are strongly decreased in the olfactory bulbs and ventral midbrain at birth, compared to wild-type littermates. Interestingly, Klf7-mutant mice show a dramatic reduction of TH-positive neurons in the olfactory bulbs, but no change in GABAergic or midbrain dopaminergic neurons. These observations raise the possibility that a lack of a KLF family member affects dopaminergic neuron development." @default.
- W2053671128 created "2016-06-24" @default.
- W2053671128 creator A5007618719 @default.
- W2053671128 creator A5009718807 @default.
- W2053671128 creator A5011689299 @default.
- W2053671128 creator A5023104356 @default.
- W2053671128 creator A5056300947 @default.
- W2053671128 creator A5062499648 @default.
- W2053671128 creator A5066037291 @default.
- W2053671128 creator A5083828029 @default.
- W2053671128 creator A5086198129 @default.
- W2053671128 creator A5088498112 @default.
- W2053671128 date "2011-02-15" @default.
- W2053671128 modified "2023-10-18" @default.
- W2053671128 title "Krüppel-like factor 7 is required for olfactory bulb dopaminergic neuron development" @default.
- W2053671128 cites W1261785331 @default.
- W2053671128 cites W1486520622 @default.
- W2053671128 cites W1487852103 @default.
- W2053671128 cites W1593988473 @default.
- W2053671128 cites W1597054100 @default.
- W2053671128 cites W1965843094 @default.
- W2053671128 cites W1967847849 @default.
- W2053671128 cites W1968034152 @default.
- W2053671128 cites W1968406762 @default.
- W2053671128 cites W1968580358 @default.
- W2053671128 cites W1975628780 @default.
- W2053671128 cites W1977152495 @default.
- W2053671128 cites W1981862471 @default.
- W2053671128 cites W1982708967 @default.
- W2053671128 cites W1983688248 @default.
- W2053671128 cites W1985645274 @default.
- W2053671128 cites W1988866946 @default.
- W2053671128 cites W1990817750 @default.
- W2053671128 cites W1999055162 @default.
- W2053671128 cites W1999275814 @default.
- W2053671128 cites W2001148131 @default.
- W2053671128 cites W2001369242 @default.
- W2053671128 cites W2004275727 @default.
- W2053671128 cites W2007170883 @default.
- W2053671128 cites W2007384933 @default.
- W2053671128 cites W2009128664 @default.
- W2053671128 cites W2012825989 @default.
- W2053671128 cites W2033816491 @default.
- W2053671128 cites W2034457280 @default.
- W2053671128 cites W2038125137 @default.
- W2053671128 cites W2049413855 @default.
- W2053671128 cites W2050054329 @default.
- W2053671128 cites W2067147530 @default.
- W2053671128 cites W2071297490 @default.
- W2053671128 cites W2071656982 @default.
- W2053671128 cites W2072496942 @default.
- W2053671128 cites W2079751838 @default.
- W2053671128 cites W2094980562 @default.
- W2053671128 cites W2095358593 @default.
- W2053671128 cites W2117506912 @default.
- W2053671128 cites W2118804397 @default.
- W2053671128 cites W2125117518 @default.
- W2053671128 cites W2151792462 @default.
- W2053671128 cites W2152092558 @default.
- W2053671128 cites W2153201445 @default.
- W2053671128 cites W2166831812 @default.
- W2053671128 cites W2409206237 @default.
- W2053671128 cites W587429664 @default.
- W2053671128 cites W648426680 @default.
- W2053671128 doi "https://doi.org/10.1016/j.yexcr.2010.11.006" @default.
- W2053671128 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21093432" @default.
- W2053671128 hasPublicationYear "2011" @default.
- W2053671128 type Work @default.
- W2053671128 sameAs 2053671128 @default.
- W2053671128 citedByCount "22" @default.
- W2053671128 countsByYear W20536711282012 @default.
- W2053671128 countsByYear W20536711282013 @default.
- W2053671128 countsByYear W20536711282014 @default.
- W2053671128 countsByYear W20536711282016 @default.
- W2053671128 countsByYear W20536711282017 @default.
- W2053671128 countsByYear W20536711282018 @default.
- W2053671128 countsByYear W20536711282020 @default.
- W2053671128 countsByYear W20536711282021 @default.
- W2053671128 countsByYear W20536711282022 @default.
- W2053671128 countsByYear W20536711282023 @default.
- W2053671128 crossrefType "journal-article" @default.
- W2053671128 hasAuthorship W2053671128A5007618719 @default.
- W2053671128 hasAuthorship W2053671128A5009718807 @default.
- W2053671128 hasAuthorship W2053671128A5011689299 @default.
- W2053671128 hasAuthorship W2053671128A5023104356 @default.
- W2053671128 hasAuthorship W2053671128A5056300947 @default.
- W2053671128 hasAuthorship W2053671128A5062499648 @default.
- W2053671128 hasAuthorship W2053671128A5066037291 @default.
- W2053671128 hasAuthorship W2053671128A5083828029 @default.
- W2053671128 hasAuthorship W2053671128A5086198129 @default.
- W2053671128 hasAuthorship W2053671128A5088498112 @default.
- W2053671128 hasConcept C104317684 @default.
- W2053671128 hasConcept C137183658 @default.
- W2053671128 hasConcept C159167319 @default.
- W2053671128 hasConcept C169760540 @default.
- W2053671128 hasConcept C201792869 @default.
- W2053671128 hasConcept C2778794669 @default.
- W2053671128 hasConcept C2780496858 @default.