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- W2053679126 abstract "The accurate mass and time tag mass spectrometry method and clustering analysis were used to compare the abundance change of 992 Yersinia pestis proteins under four contrasting growth conditions (26 and 37 degrees C, with or without Ca2+) that mimicked growth states in either a flea vector or mammalian host. Eighty-nine proteins were observed to have similar abundance change profiles to 29 known virulence associated proteins, providing identification of additional biomarker candidates. Eighty-seven hypothetical proteins, which clustered into 5 distinct clusters of like-protein abundance change, were identified as unique biomarkers related specifically to growth condition." @default.
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- W2053679126 date "2006-09-27" @default.
- W2053679126 modified "2023-09-25" @default.
- W2053679126 title "Biomarker Candidate Identification in <i>Yersinia </i><i>p</i><i>estis</i> Using Organism-Wide Semiquantitative Proteomics" @default.
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- W2053679126 doi "https://doi.org/10.1021/pr060179y" @default.
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