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• W2053682040 abstract "Much research on oestrogens has focused on their long-term action, exerting behavioural effects within hours to days through gene transcription. Oestrogens also affect behaviour on a much shorter time scale. These rapid effects are assumed to occur through cell signalling and can elicit a behavioural effect as early as 15 min after treatment. These effects on behaviour have primarily been explored through the action of oestradiol at three well-known oestrogen receptors (ERs): ERα, ERβ and the more recently described G protein-coupled ER1 (GPER1). The rapid effects of oestradiol and ER agonists have been tested on both social and nonsocial learning paradigms. Social learning refers to a paradigm in which an animal acquires information and modifies its behaviour based on observation of another animal, commonly studied using the social transmission of food preferences paradigm. When administered shortly before testing, oestradiol rapidly improves social learning on this task, although no ER agonist has definitive, comparable improving effects. Some evidence points to GPER1, whereas ERα impairs, and ERβ activation has no effect on social learning. Conversely, ERα and GPER1 play a larger role than ERβ in the rapid improving effect of oestrogens on nonsocial learning, including social and object recognition. In addition, when administered immediately post-acquisition, oestrogens also rapidly improve memory consolidation in a variety of learning paradigms: object recognition, object placement, inhibitory avoidance and the Morris water maze, indicating that oestradiol affects the consolidation of multiple types of memory. Evidence suggests that these improvements are the result of oestrogens acting in the dorsal hippocampus where selective activation of all three ERs shows rapid improving effects on spatial learning comparable to oestradiol. However, the hippocampus is not necessary for rapid oestradiol improvements on social recognition. Although acute treatment with oestradiol enhances learning and memory on various social and nonsocial learning paradigms, the specific ERs play different roles in each type of learning. Future research should aim to further determine the roles of ERs with respect to the enhancing effects of oestradiol on learning and memory, and also determine where in the brain oestradiol acts to affect social and nonsocial learning." @default.
• W2053682040 created "2016-06-24" @default.
• W2053682040 creator A5000960833 @default.
• W2053682040 creator A5032328699 @default.
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• W2053682040 date "2013-10-28" @default.
• W2053682040 modified "2023-09-23" @default.
• W2053682040 title "Rapid Oestrogenic Regulation of Social and Nonsocial Learning" @default.
• W2053682040 cites W112593876 @default.
• W2053682040 cites W1954468845 @default.
• W2053682040 cites W1965657782 @default.
• W2053682040 cites W1966660173 @default.
• W2053682040 cites W1970636571 @default.
• W2053682040 cites W1970723205 @default.
• W2053682040 cites W1971626420 @default.
• W2053682040 cites W1972814152 @default.
• W2053682040 cites W1973023891 @default.
• W2053682040 cites W1974452009 @default.
• W2053682040 cites W1977812314 @default.
• W2053682040 cites W1978528899 @default.
• W2053682040 cites W1979466191 @default.
• W2053682040 cites W1980574091 @default.
• W2053682040 cites W1982038091 @default.
• W2053682040 cites W1983538594 @default.
• W2053682040 cites W1984242980 @default.
• W2053682040 cites W1987549073 @default.
• W2053682040 cites W1989578143 @default.
• W2053682040 cites W1989849786 @default.
• W2053682040 cites W1990015984 @default.
• W2053682040 cites W1990382521 @default.
• W2053682040 cites W1990540942 @default.
• W2053682040 cites W1992285770 @default.
• W2053682040 cites W1992665822 @default.
• W2053682040 cites W1992716372 @default.
• W2053682040 cites W1993176591 @default.
• W2053682040 cites W1998007696 @default.
• W2053682040 cites W1998131521 @default.
• W2053682040 cites W1999055090 @default.
• W2053682040 cites W2004057308 @default.
• W2053682040 cites W2004065307 @default.
• W2053682040 cites W2004598179 @default.
• W2053682040 cites W2005016581 @default.
• W2053682040 cites W2005139532 @default.
• W2053682040 cites W2005602845 @default.
• W2053682040 cites W2009057820 @default.
• W2053682040 cites W2009782005 @default.
• W2053682040 cites W2010732872 @default.
• W2053682040 cites W2012892145 @default.
• W2053682040 cites W2014213229 @default.
• W2053682040 cites W2017181431 @default.
• W2053682040 cites W2018601731 @default.
• W2053682040 cites W2018947184 @default.
• W2053682040 cites W2020338570 @default.
• W2053682040 cites W2021451131 @default.
• W2053682040 cites W2024364396 @default.
• W2053682040 cites W2024960695 @default.
• W2053682040 cites W2025557556 @default.
• W2053682040 cites W2025783926 @default.
• W2053682040 cites W2028330147 @default.
• W2053682040 cites W2029745222 @default.
• W2053682040 cites W2032679251 @default.
• W2053682040 cites W2032843033 @default.
• W2053682040 cites W2034261103 @default.
• W2053682040 cites W2034627732 @default.
• W2053682040 cites W2034675086 @default.
• W2053682040 cites W2038873736 @default.
• W2053682040 cites W2040452349 @default.
• W2053682040 cites W2042733452 @default.
• W2053682040 cites W2047177369 @default.
• W2053682040 cites W2048310604 @default.
• W2053682040 cites W2048822470 @default.
• W2053682040 cites W2049111053 @default.
• W2053682040 cites W2050306241 @default.
• W2053682040 cites W2052063877 @default.
• W2053682040 cites W2053626685 @default.
• W2053682040 cites W2053682040 @default.
• W2053682040 cites W2053817786 @default.
• W2053682040 cites W2054420201 @default.
• W2053682040 cites W2056021502 @default.
• W2053682040 cites W2056400970 @default.
• W2053682040 cites W2056695794 @default.
• W2053682040 cites W2057364425 @default.
• W2053682040 cites W2057598257 @default.
• W2053682040 cites W2059072714 @default.
• W2053682040 cites W2060080235 @default.
• W2053682040 cites W2060889804 @default.
• W2053682040 cites W2063112960 @default.
• W2053682040 cites W2063860385 @default.
• W2053682040 cites W2064407977 @default.
• W2053682040 cites W2065163181 @default.
• W2053682040 cites W2066915690 @default.
• W2053682040 cites W2067642579 @default.
• W2053682040 cites W2068972835 @default.
• W2053682040 cites W2069519651 @default.
• W2053682040 cites W2069849707 @default.
• W2053682040 cites W2073883348 @default.
• W2053682040 cites W2075133445 @default.

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