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• W2053703909 abstract "The derivation of cross-correlation functions from single-channel dwell (open and closed) times is described. Simulation of single-channel data for simple gating models, alongside theoretical treatment, is used to demonstrate the relationship of cross-correlation functions to underlying gating mechanisms. It is shown that time irreversibility of gating kinetics may be revealed in cross-correlation functions. Application of cross-correlation function analysis to data derived from the locust muscle glutamate receptor-channel provides evidence for multiple gateway states and time reversibility of gating. A model for the gating of this channel is used to show the effect of omission of brief channel events on cross-correlation functions." @default.
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• W2053703909 date "1988-08-01" @default.
• W2053703909 modified "2023-10-15" @default.
• W2053703909 title "The use of dwell time cross-correlation functions to study single-ion channel gating kinetics" @default.
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• W2053703909 doi "https://doi.org/10.1016/s0006-3495(88)82961-8" @default.
• W2053703909 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1330298" @default.
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