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- W2053705226 abstract "A significant contribution to cancer treatment occurred with the introduction of cisplatin in phase I clinical trials approximately 16 years ago. The potentially life-threatening side effect of renal toxicity has been controlled with adequate hydration and diuresis. Nausea and vomiting have become the most common toxicities associated with cisplatin. Clinical research trials are ongoing in an attempt to identify effective antiemetic regimens.1 As patients voiced a preference for outpatient management, parameters were established for selecting good candidates for outpatient cisplatin therapy, with the safety issue a foremost consideration. Increasingly, physicians expressed confidence in being able to safely treat patients in the outpatient facility, which led to an extension of cisplatin therapy in the office setting. Pretreatment planning is necessary to provide an adequate physical setting, hire and train sufficient staff, develop policies and procedures, and establish education programs to assist patients in self-care management at home. Clearly, cisplatin has become a valuable cytotoxic agent in the hands of skilled oncologists who are able to manage patients outside of the hospital, thus enabling the resumption of a more normal life-style." @default.
- W2053705226 created "2016-06-24" @default.
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- W2053705226 date "1987-02-01" @default.
- W2053705226 modified "2023-09-26" @default.
- W2053705226 title "Considerations in the outpatient and office administration of cisplatin" @default.
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- W2053705226 doi "https://doi.org/10.1016/0749-2081(87)90021-0" @default.
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