FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2053707539> ?p ?o ?g. }

• W2053707539 endingPage "1323" @default.
• W2053707539 startingPage "1318" @default.
• W2053707539 abstract "© The Author 2015. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved. Introduction: Nicotine replacement therapy (NRT) helps nonpregnant smokers quit, but there is no evidence that standard dose NRT is effective in pregnancy. As nicotine metabolism increases in pregnancy, this could reduce NRT efficacy. Using the ratio of trans-3'-hydroxycotinine to cotinine, the nicotine metabolite ratio (NMR), we investigated relationships between the rate of nicotine metabolism, maternal characteristics and smoking cessation in pregnant women recruited to a randomized controlled trial of NRT. Methods: Data from 1,050 pregnant smokers in the Smoking, Nicotine and Pregnancy trial who were of 12-24 weeks gestation had exhaled carbon monoxide readings of ≥8 ppm at recruitment and who were randomized to NRT or placebo patches were used. Linear and logistic regression investigated associations between maternal characteristics and NMR and also between NMR and subsequent validated cessation from smoking. Results: Six hundred and sixty-two women (63%) provided blood samples for NMR estimation. Higher NMR was associated with increased cigarette consumption prior to pregnancy. At 1 month (odds ratio [OR] = 0.87; 95% CI = 0.76-0.99; p = .043) and delivery (OR = 0.79; 95% CI = 0.66-0.95; p = .010), there was a significant negative association between a 0.1 unit increase in NMR and odds of achieving cessation after adjusting for possible confounders. There was no evidence for an interaction between a 0.1 unit increase in NMR and treatment assignment on the odds of cessation at 1 month post-quit date (p = .556). Conclusion: Pregnant women who metabolize nicotine more rapidly are less likely to achieve cessation when they try to quit smoking. There is no evidence that NRT is more effective in women who metabolize nicotine more slowly." @default.
• W2053707539 created "2016-06-24" @default.
• W2053707539 creator A5013599374 @default.
• W2053707539 creator A5032201852 @default.
• W2053707539 creator A5046300554 @default.
• W2053707539 creator A5073177648 @default.
• W2053707539 creator A5088707049 @default.
• W2053707539 date "2015-01-14" @default.
• W2053707539 modified "2023-10-18" @default.
• W2053707539 title "The Nicotine Metabolite Ratio in Pregnancy Measured by<i>trans</i>-3′-Hydroxycotinine to Cotinine Ratio: Characteristics and Relationship With Smoking Cessation: Table 1." @default.
• W2053707539 cites W1970089074 @default.
• W2053707539 cites W1983882432 @default.
• W2053707539 cites W1984098999 @default.
• W2053707539 cites W1984300319 @default.
• W2053707539 cites W1994405711 @default.
• W2053707539 cites W2012763305 @default.
• W2053707539 cites W2015234747 @default.
• W2053707539 cites W2015259201 @default.
• W2053707539 cites W2020466267 @default.
• W2053707539 cites W2030471578 @default.
• W2053707539 cites W2035501540 @default.
• W2053707539 cites W2051651195 @default.
• W2053707539 cites W2063280109 @default.
• W2053707539 cites W2082783124 @default.
• W2053707539 cites W2084081336 @default.
• W2053707539 cites W2101566038 @default.
• W2053707539 cites W2103438776 @default.
• W2053707539 cites W2109104618 @default.
• W2053707539 cites W2110919611 @default.
• W2053707539 cites W2116438644 @default.
• W2053707539 cites W2119675051 @default.
• W2053707539 cites W2129271383 @default.
• W2053707539 cites W2130452710 @default.
• W2053707539 cites W2132635946 @default.
• W2053707539 cites W2138106394 @default.
• W2053707539 cites W2158006177 @default.
• W2053707539 cites W2168788155 @default.
• W2053707539 cites W2169463741 @default.
• W2053707539 cites W4211257394 @default.
• W2053707539 doi "https://doi.org/10.1093/ntr/ntu342" @default.
• W2053707539 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25589677" @default.
• W2053707539 hasPublicationYear "2015" @default.
• W2053707539 type Work @default.
• W2053707539 sameAs 2053707539 @default.
• W2053707539 citedByCount "21" @default.
• W2053707539 countsByYear W20537075392015 @default.
• W2053707539 countsByYear W20537075392016 @default.
• W2053707539 countsByYear W20537075392017 @default.
• W2053707539 countsByYear W20537075392018 @default.
• W2053707539 countsByYear W20537075392019 @default.
• W2053707539 countsByYear W20537075392020 @default.
• W2053707539 countsByYear W20537075392021 @default.
• W2053707539 countsByYear W20537075392022 @default.
• W2053707539 countsByYear W20537075392023 @default.
• W2053707539 crossrefType "journal-article" @default.
• W2053707539 hasAuthorship W2053707539A5013599374 @default.
• W2053707539 hasAuthorship W2053707539A5032201852 @default.
• W2053707539 hasAuthorship W2053707539A5046300554 @default.
• W2053707539 hasAuthorship W2053707539A5073177648 @default.
• W2053707539 hasAuthorship W2053707539A5088707049 @default.
• W2053707539 hasConcept C126322002 @default.
• W2053707539 hasConcept C131872663 @default.
• W2053707539 hasConcept C142724271 @default.
• W2053707539 hasConcept C2776319443 @default.
• W2053707539 hasConcept C2777477808 @default.
• W2053707539 hasConcept C2777843972 @default.
• W2053707539 hasConcept C2779547902 @default.
• W2053707539 hasConcept C44249647 @default.
• W2053707539 hasConcept C71924100 @default.
• W2053707539 hasConceptScore W2053707539C126322002 @default.
• W2053707539 hasConceptScore W2053707539C131872663 @default.
• W2053707539 hasConceptScore W2053707539C142724271 @default.
• W2053707539 hasConceptScore W2053707539C2776319443 @default.
• W2053707539 hasConceptScore W2053707539C2777477808 @default.
• W2053707539 hasConceptScore W2053707539C2777843972 @default.
• W2053707539 hasConceptScore W2053707539C2779547902 @default.
• W2053707539 hasConceptScore W2053707539C44249647 @default.
• W2053707539 hasConceptScore W2053707539C71924100 @default.
• W2053707539 hasIssue "11" @default.
• W2053707539 hasLocation W20537075391 @default.
• W2053707539 hasOpenAccess W2053707539 @default.
• W2053707539 hasPrimaryLocation W20537075391 @default.
• W2053707539 hasRelatedWork W151590255 @default.
• W2053707539 hasRelatedWork W2011700094 @default.
• W2053707539 hasRelatedWork W2012474406 @default.
• W2053707539 hasRelatedWork W2020542613 @default.
• W2053707539 hasRelatedWork W2079256639 @default.
• W2053707539 hasRelatedWork W2130073093 @default.
• W2053707539 hasRelatedWork W2157335019 @default.
• W2053707539 hasRelatedWork W2343675750 @default.
• W2053707539 hasRelatedWork W2413584315 @default.
• W2053707539 hasRelatedWork W2991275368 @default.
• W2053707539 hasVolume "17" @default.
• W2053707539 isParatext "false" @default.
• W2053707539 isRetracted "false" @default.
• W2053707539 magId "2053707539" @default.
• W2053707539 workType "article" @default.