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- W2053716080 abstract "Enantiomerically pure fluorinated isoindoline and dihydroisoquinoline scaffolds have been prepared through a diastereoselective addition of fluorinated nucleophiles to Ellman’s N-(tert-butanesulfinyl)imines followed by a sequence of Sonogashira cross-coupling/gold(I)-catalyzed cycloisomerization of the corresponding carbamate. A more favored 5-exo-dig mechanism was observed mainly due to an electronic effect of the fluorinated group." @default.
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- W2053716080 date "2013-01-29" @default.
- W2053716080 modified "2023-10-09" @default.
- W2053716080 title "Gold-Catalyzed Intramolecular Hydroamination of <i>o</i>-Alkynylbenzyl Carbamates: A Route to Chiral Fluorinated Isoindoline and Isoquinoline Derivatives" @default.
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- W2053716080 doi "https://doi.org/10.1021/ol3035142" @default.
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