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• W2053751588 abstract "Polycystins are a distinct family of integral membrane proteins, related by sequence and structural homology. These proteins play important roles in organ morphogenesis and function, and mutations in two of the five known members cause a common renal cystic disease. Recent data on the function of polycystins have revealed them to be Ca2+-permeable cation channels and putative ion-channel regulators. Their roles in the regulation of intracellular Ca2+ concentration and in polycystic kidney disease are discussed." @default.
• W2053751588 created "2016-06-24" @default.
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• W2053751588 date "2001-11-01" @default.
• W2053751588 modified "2023-10-14" @default.
• W2053751588 title "Polycystin channels and kidney disease" @default.
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• W2053751588 doi "https://doi.org/10.1016/s0165-6147(00)01832-0" @default.
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