Matches in SemOpenAlex for { <https://semopenalex.org/work/W2053770145> ?p ?o ?g. }
- W2053770145 endingPage "2477" @default.
- W2053770145 startingPage "2471" @default.
- W2053770145 abstract "It has been shown that reactivity against major histocompatibility complex (MHC) class II-associated Mlsa determinants is mainly mediated by CD4+ V beta 6+ T cells. 3F9 is a CD8+ CTL clone which is specific for the alloantigen H-2Db. While 3F9 is V beta 6+, it is not Mlsa reactive, presumably because it does not express CD4. 3F9 utilizes the same T cell receptor (TcR) V alpha V beta combination as LB2, a CD4+ T helper clone specific for chicken red blood cells (cRBC)/I-Ab and yet differs from LB2 in the junctional sequences in both TcR chains. CD4+ CD8- and CD4-CD8- hybridomas expressing the 3F9 TcR were tested for reactivity against Mlsa and cRBC/I-Ab. Only the CD4+CD8- hybridomas were Mlsa reactive, and antibody inhibition studies revealed that this reactivity was both CD4 and MHC class II dependent. Therefore the expression of the CD4 molecule can make an MHC class I-restricted TcR Mlsa reactive. Neither type of hybridoma reacted against cRBC, thus the main difference in the antigen reactivity between 3F9 and LB2 lies in the TcR junctional regions." @default.
- W2053770145 created "2016-06-24" @default.
- W2053770145 creator A5000800493 @default.
- W2053770145 creator A5009783885 @default.
- W2053770145 creator A5014872117 @default.
- W2053770145 creator A5060222946 @default.
- W2053770145 date "1990-11-01" @default.
- W2053770145 modified "2023-10-02" @default.
- W2053770145 title "Expression of CD4 can confer major histocompatibility complex class II-associated superantigen reactivity upon a T cell receptor derived from a CD8-dependent cytotoxic T lymphocyte clone" @default.
- W2053770145 cites W1480489408 @default.
- W2053770145 cites W1963569988 @default.
- W2053770145 cites W1966897395 @default.
- W2053770145 cites W1970930845 @default.
- W2053770145 cites W1978623413 @default.
- W2053770145 cites W1982920370 @default.
- W2053770145 cites W1985774274 @default.
- W2053770145 cites W1988363849 @default.
- W2053770145 cites W1990316427 @default.
- W2053770145 cites W1990567364 @default.
- W2053770145 cites W2020055566 @default.
- W2053770145 cites W2024441858 @default.
- W2053770145 cites W2026729878 @default.
- W2053770145 cites W2027306447 @default.
- W2053770145 cites W2029993034 @default.
- W2053770145 cites W2031011895 @default.
- W2053770145 cites W2034760746 @default.
- W2053770145 cites W2035444732 @default.
- W2053770145 cites W2036314272 @default.
- W2053770145 cites W2044063726 @default.
- W2053770145 cites W2044309960 @default.
- W2053770145 cites W2049596623 @default.
- W2053770145 cites W2055271950 @default.
- W2053770145 cites W2055282100 @default.
- W2053770145 cites W2055433316 @default.
- W2053770145 cites W2055584900 @default.
- W2053770145 cites W2056388065 @default.
- W2053770145 cites W2060825573 @default.
- W2053770145 cites W2061227314 @default.
- W2053770145 cites W2064390120 @default.
- W2053770145 cites W2064484362 @default.
- W2053770145 cites W2066347271 @default.
- W2053770145 cites W2070437307 @default.
- W2053770145 cites W2070442757 @default.
- W2053770145 cites W2079402517 @default.
- W2053770145 cites W2080052508 @default.
- W2053770145 cites W2086764321 @default.
- W2053770145 cites W2089418619 @default.
- W2053770145 cites W2096273252 @default.
- W2053770145 cites W2098446605 @default.
- W2053770145 cites W2101929599 @default.
- W2053770145 cites W2115741650 @default.
- W2053770145 cites W2129691747 @default.
- W2053770145 cites W2132419380 @default.
- W2053770145 cites W2139330598 @default.
- W2053770145 cites W2140443312 @default.
- W2053770145 cites W2141906846 @default.
- W2053770145 cites W2159108645 @default.
- W2053770145 cites W2166200718 @default.
- W2053770145 cites W2173828780 @default.
- W2053770145 cites W2176944210 @default.
- W2053770145 cites W2314854553 @default.
- W2053770145 cites W2530023051 @default.
- W2053770145 doi "https://doi.org/10.1002/eji.1830201117" @default.
- W2053770145 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2123792" @default.
- W2053770145 hasPublicationYear "1990" @default.
- W2053770145 type Work @default.
- W2053770145 sameAs 2053770145 @default.
- W2053770145 citedByCount "1" @default.
- W2053770145 crossrefType "journal-article" @default.
- W2053770145 hasAuthorship W2053770145A5000800493 @default.
- W2053770145 hasAuthorship W2053770145A5009783885 @default.
- W2053770145 hasAuthorship W2053770145A5014872117 @default.
- W2053770145 hasAuthorship W2053770145A5060222946 @default.
- W2053770145 hasConcept C104317684 @default.
- W2053770145 hasConcept C147483822 @default.
- W2053770145 hasConcept C147969180 @default.
- W2053770145 hasConcept C153911025 @default.
- W2053770145 hasConcept C154317977 @default.
- W2053770145 hasConcept C167672396 @default.
- W2053770145 hasConcept C170627219 @default.
- W2053770145 hasConcept C19317047 @default.
- W2053770145 hasConcept C195616568 @default.
- W2053770145 hasConcept C197695756 @default.
- W2053770145 hasConcept C202751555 @default.
- W2053770145 hasConcept C203014093 @default.
- W2053770145 hasConcept C207936829 @default.
- W2053770145 hasConcept C2776090121 @default.
- W2053770145 hasConcept C2992881475 @default.
- W2053770145 hasConcept C36333154 @default.
- W2053770145 hasConcept C54355233 @default.
- W2053770145 hasConcept C81089528 @default.
- W2053770145 hasConcept C86803240 @default.
- W2053770145 hasConcept C8891405 @default.
- W2053770145 hasConceptScore W2053770145C104317684 @default.
- W2053770145 hasConceptScore W2053770145C147483822 @default.
- W2053770145 hasConceptScore W2053770145C147969180 @default.
- W2053770145 hasConceptScore W2053770145C153911025 @default.
- W2053770145 hasConceptScore W2053770145C154317977 @default.