FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2053812062> ?p ?o ?g. }

• W2053812062 endingPage "95" @default.
• W2053812062 startingPage "90" @default.
• W2053812062 abstract "The ubiquitin-proteasome system is the major non-lysosymal system for degrading proteins in the cell; the work leading to its discovery was awarded the Nobel Prize in Chemistry in 2004. In addition to small ubiquitin-like modifiers (e.g. Sumo and Nedd8), ubiquitin is involved in the complex regulation of the levels and function of many proteins and signaling pathways involved in determining cell fate. The cell death regulatory proteins, such as Bcl-2 family proteins and caspases are targeted for degradation by the ubiquitin proteasome system (UPS). In addition to mediating the degradation of proteins, the UPS regulates function and translocation of proteins, many of which play a role in the determination of cell fate. For example the UPS can regulate the activity of transcription factors, such as P53, NF-kappaB and HIF-1 alpha, which control the expression of protein mediators of cell death. Aberrant UPS function has been reported in multiple neuropathologies including Parkinson's diseases and ischemia. With the number of ubiquitin conjugating and de-conjugating enzymes reaching close to the levels of protein kinases and phosphatases, it is clear that ubiquitination is an important biological regulatory step for proteins." @default.
• W2053812062 created "2016-06-24" @default.
• W2053812062 creator A5011220438 @default.
• W2053812062 creator A5070403963 @default.
• W2053812062 creator A5083165869 @default.
• W2053812062 creator A5086041302 @default.
• W2053812062 date "2008-02-01" @default.
• W2053812062 modified "2023-09-26" @default.
• W2053812062 title "Ubiquitin–proteasome system as a modulator of cell fate" @default.
• W2053812062 cites W1573531091 @default.
• W2053812062 cites W1832030339 @default.
• W2053812062 cites W1967391569 @default.
• W2053812062 cites W1971576886 @default.
• W2053812062 cites W1974379210 @default.
• W2053812062 cites W1978116926 @default.
• W2053812062 cites W1983592427 @default.
• W2053812062 cites W1984169187 @default.
• W2053812062 cites W1986906983 @default.
• W2053812062 cites W1989598939 @default.
• W2053812062 cites W1990752073 @default.
• W2053812062 cites W1991634033 @default.
• W2053812062 cites W1993170641 @default.
• W2053812062 cites W1995800473 @default.
• W2053812062 cites W2003955184 @default.
• W2053812062 cites W2005909927 @default.
• W2053812062 cites W2007687005 @default.
• W2053812062 cites W2008355658 @default.
• W2053812062 cites W2014231458 @default.
• W2053812062 cites W2014726590 @default.
• W2053812062 cites W2017632687 @default.
• W2053812062 cites W2017728303 @default.
• W2053812062 cites W2018607587 @default.
• W2053812062 cites W2019522410 @default.
• W2053812062 cites W2019761433 @default.
• W2053812062 cites W2027976018 @default.
• W2053812062 cites W2031674170 @default.
• W2053812062 cites W2038753750 @default.
• W2053812062 cites W2042319759 @default.
• W2053812062 cites W2048370637 @default.
• W2053812062 cites W2049046201 @default.
• W2053812062 cites W2050745715 @default.
• W2053812062 cites W2052553321 @default.
• W2053812062 cites W2054998458 @default.
• W2053812062 cites W2059569571 @default.
• W2053812062 cites W2060075812 @default.
• W2053812062 cites W2063211255 @default.
• W2053812062 cites W2068696470 @default.
• W2053812062 cites W2073133734 @default.
• W2053812062 cites W2074545297 @default.
• W2053812062 cites W2081843959 @default.
• W2053812062 cites W2083068595 @default.
• W2053812062 cites W2083644948 @default.
• W2053812062 cites W2085483520 @default.
• W2053812062 cites W2086688096 @default.
• W2053812062 cites W2087087126 @default.
• W2053812062 cites W2091366475 @default.
• W2053812062 cites W2098902167 @default.
• W2053812062 cites W2110780830 @default.
• W2053812062 cites W2115023989 @default.
• W2053812062 cites W2116786855 @default.
• W2053812062 cites W2120784935 @default.
• W2053812062 cites W2122044343 @default.
• W2053812062 cites W2126390187 @default.
• W2053812062 cites W2128786825 @default.
• W2053812062 cites W2131575598 @default.
• W2053812062 cites W2151538478 @default.
• W2053812062 cites W2166109719 @default.
• W2053812062 cites W5959882 @default.
• W2053812062 doi "https://doi.org/10.1016/j.coph.2007.09.010" @default.
• W2053812062 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2265078" @default.
• W2053812062 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17981502" @default.
• W2053812062 hasPublicationYear "2008" @default.
• W2053812062 type Work @default.
• W2053812062 sameAs 2053812062 @default.
• W2053812062 citedByCount "70" @default.
• W2053812062 countsByYear W20538120622012 @default.
• W2053812062 countsByYear W20538120622013 @default.
• W2053812062 countsByYear W20538120622014 @default.
• W2053812062 countsByYear W20538120622015 @default.
• W2053812062 countsByYear W20538120622016 @default.
• W2053812062 countsByYear W20538120622017 @default.
• W2053812062 countsByYear W20538120622018 @default.
• W2053812062 countsByYear W20538120622019 @default.
• W2053812062 countsByYear W20538120622020 @default.
• W2053812062 countsByYear W20538120622021 @default.
• W2053812062 countsByYear W20538120622022 @default.
• W2053812062 countsByYear W20538120622023 @default.
• W2053812062 crossrefType "journal-article" @default.
• W2053812062 hasAuthorship W2053812062A5011220438 @default.
• W2053812062 hasAuthorship W2053812062A5070403963 @default.
• W2053812062 hasAuthorship W2053812062A5083165869 @default.
• W2053812062 hasAuthorship W2053812062A5086041302 @default.
• W2053812062 hasBestOaLocation W20538120622 @default.
• W2053812062 hasConcept C102658986 @default.
• W2053812062 hasConcept C104317684 @default.
• W2053812062 hasConcept C131312102 @default.
• W2053812062 hasConcept C134459356 @default.
• W2053812062 hasConcept C14036430 @default.

• next