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- W2053828054 abstract "1. The effects of Cytochalasin B, glucagon and theophylline, in the presence of a high concentration of glucose (5 mg/ml), on insulin release from pancreatic (splenic) islets of a lizard (Anolis carolinensis) were studied in an in vitro perifusion system. 2. Theophylline (10−3 M) plus glucagon (1 μg/ml) effected a significant increase in insulin secretion, suggesting adenosine 3',5'-monophosphate modulation of insulin release from saurian pancreatic B cells. 3. A biphasic pattern of insulin release, similar to that found with glucose alone, was observed with Cytochalasin B (5 μg/ml) included in the perifusion medium, but the amount of insulin secreted was significantly greater than with glucose alone. 4. Cytochalasin B in the presence of theophylline plus glucagon resulted in a monophasic pattern and essentially linear rise in insulin release." @default.
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- W2053828054 date "1974-01-01" @default.
- W2053828054 modified "2023-09-23" @default.
- W2053828054 title "Effects of cytochalasin B and other agents on insulin secretion from saurian islets" @default.
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- W2053828054 doi "https://doi.org/10.1016/0300-9629(74)90470-8" @default.
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