FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2053831452> ?p ?o ?g. }

• W2053831452 endingPage "439" @default.
• W2053831452 startingPage "430" @default.
• W2053831452 abstract "Antigenic encounter by T cells induces immunological synapse formation and T-cell activation. Using different concentrations of toxic shock syndrome toxin-1 (TSST-1) as stimulus, we examined the capacities of dendritic cells (DC) and macrophages (Mphi) to prime syngeneic naive T cells. DCs were, under all experimental settings, more efficient than Mphi at clustering T cells. Translocation of the T-cell receptor (TCR) to the contact area was found to be induced by DCs, as well as by Mphi, in an antigen-dependent manner, although Mphi were less efficient at inducing TCR translocation. Capping of protein kinase C theta (PKCtheta) was also antigen dependent but induced exclusively by DCs. Likewise, DCs were found to be more potent inducers of interleukin-2 (IL-2) production and proliferation of naive T cells than Mphi. After 3 days of culture, DCs presenting 100 ng/ml TSST-1 induced interferon-gamma (IFN-gamma)-secreting cells, whereas Mphi did not. After 7 days of culture, DCs presenting 0.1 ng/ml TSST-1, and Mphi presenting high (as well as low) doses of TSST-1, induced IL-4-producing cells. We therefore provide evidence to show that antigen dose, type of antigen-presenting cell and time of differentiation can contribute to T-cell differentiation." @default.
• W2053831452 created "2016-06-24" @default.
• W2053831452 creator A5016829123 @default.
• W2053831452 creator A5020854274 @default.
• W2053831452 creator A5052796137 @default.
• W2053831452 creator A5076814449 @default.
• W2053831452 creator A5089492365 @default.
• W2053831452 date "2003-11-24" @default.
• W2053831452 modified "2023-10-14" @default.
• W2053831452 title "Antigen dose, type of antigen-presenting cell and time of differentiation contribute to the T helper 1/T helper 2 polarization of naive T cells" @default.
• W2053831452 cites W1488377901 @default.
• W2053831452 cites W1511991731 @default.
• W2053831452 cites W1518539840 @default.
• W2053831452 cites W1528831675 @default.
• W2053831452 cites W1562441478 @default.
• W2053831452 cites W1585445496 @default.
• W2053831452 cites W1609713897 @default.
• W2053831452 cites W1811262219 @default.
• W2053831452 cites W1839311906 @default.
• W2053831452 cites W1917000450 @default.
• W2053831452 cites W1966397350 @default.
• W2053831452 cites W1978375561 @default.
• W2053831452 cites W1988019232 @default.
• W2053831452 cites W1988114488 @default.
• W2053831452 cites W1994824543 @default.
• W2053831452 cites W1995636937 @default.
• W2053831452 cites W2012871894 @default.
• W2053831452 cites W2020455973 @default.
• W2053831452 cites W2025219269 @default.
• W2053831452 cites W2028968136 @default.
• W2053831452 cites W2032242870 @default.
• W2053831452 cites W2040066315 @default.
• W2053831452 cites W2045219244 @default.
• W2053831452 cites W2046860197 @default.
• W2053831452 cites W2054894258 @default.
• W2053831452 cites W2055669282 @default.
• W2053831452 cites W2066320353 @default.
• W2053831452 cites W2077579077 @default.
• W2053831452 cites W2092109378 @default.
• W2053831452 cites W2093138544 @default.
• W2053831452 cites W2096234619 @default.
• W2053831452 cites W2099989392 @default.
• W2053831452 cites W2100699905 @default.
• W2053831452 cites W2106007373 @default.
• W2053831452 cites W2106645663 @default.
• W2053831452 cites W2107307935 @default.
• W2053831452 cites W2111910803 @default.
• W2053831452 cites W2114639640 @default.
• W2053831452 cites W2118367937 @default.
• W2053831452 cites W2121236896 @default.
• W2053831452 cites W2124116262 @default.
• W2053831452 cites W2127800073 @default.
• W2053831452 cites W2135252042 @default.
• W2053831452 cites W2139771735 @default.
• W2053831452 cites W2141895910 @default.
• W2053831452 cites W2143669305 @default.
• W2053831452 cites W2144518949 @default.
• W2053831452 cites W2148352720 @default.
• W2053831452 cites W2151901006 @default.
• W2053831452 cites W2155158134 @default.
• W2053831452 cites W2158619692 @default.
• W2053831452 cites W2160655212 @default.
• W2053831452 cites W2163294735 @default.
• W2053831452 cites W2163570329 @default.
• W2053831452 cites W2163725321 @default.
• W2053831452 cites W2164025040 @default.
• W2053831452 cites W4243223027 @default.
• W2053831452 doi "https://doi.org/10.1111/j.1365-2567.2003.01758.x" @default.
• W2053831452 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1783073" @default.
• W2053831452 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14632640" @default.
• W2053831452 hasPublicationYear "2003" @default.
• W2053831452 type Work @default.
• W2053831452 sameAs 2053831452 @default.
• W2053831452 citedByCount "35" @default.
• W2053831452 countsByYear W20538314522012 @default.
• W2053831452 countsByYear W20538314522014 @default.
• W2053831452 countsByYear W20538314522015 @default.
• W2053831452 countsByYear W20538314522016 @default.
• W2053831452 countsByYear W20538314522017 @default.
• W2053831452 countsByYear W20538314522018 @default.
• W2053831452 countsByYear W20538314522019 @default.
• W2053831452 countsByYear W20538314522020 @default.
• W2053831452 countsByYear W20538314522021 @default.
• W2053831452 countsByYear W20538314522022 @default.
• W2053831452 crossrefType "journal-article" @default.
• W2053831452 hasAuthorship W2053831452A5016829123 @default.
• W2053831452 hasAuthorship W2053831452A5020854274 @default.
• W2053831452 hasAuthorship W2053831452A5052796137 @default.
• W2053831452 hasAuthorship W2053831452A5076814449 @default.
• W2053831452 hasAuthorship W2053831452A5089492365 @default.
• W2053831452 hasBestOaLocation W20538314522 @default.
• W2053831452 hasConcept C129374314 @default.
• W2053831452 hasConcept C147483822 @default.
• W2053831452 hasConcept C149532602 @default.
• W2053831452 hasConcept C153911025 @default.
• W2053831452 hasConcept C154317977 @default.
• W2053831452 hasConcept C167672396 @default.
• W2053831452 hasConcept C19317047 @default.

• next