Matches in SemOpenAlex for { <https://semopenalex.org/work/W2053847588> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2053847588 endingPage "52" @default.
- W2053847588 startingPage "47" @default.
- W2053847588 abstract "In the last few years, identifications of drugs in archaeological human remains were reported several times but comments on the reliability of the data were often missing. To obtain valid data, in particular on nicotine residues in ancient bones, two skeletal series were analyzed and environmental influences on the results estimated in an exposure experiment. Bone samples from the early modern age (18th century, Goslar, Germany) and from the Bronze Age (Lichtenstein Cave, Germany) were analyzed for the tobacco alkaloid and its major metabolite, cotinine. In 22 out of 34 femur samples of the Goslar series, trace amounts of nicotine were found, but no cotinine, the major metabolite. Its finding would have proved the use of tobacco in the historic population, whereas the mere discovery of nicotine cannot discriminate between endogenous material and that resulting from a contamination during the sample treatment or museum storage. This points to the necessity of further pilot studies for long-term persistence, since it was not clarified whether insufficient accumulation or poor stability may have prevented the detection of cotinine. The magnitude of a possible nicotine deposition was estimated in a control exposure experiment. A Bronze Age bone sample that definitely contained no nicotine, as proven by pretests, was exposed to environmental tobacco smoke for six weeks and then analyzed. In one part, 11.6 ng g m 1 nicotine were estimated and, in another, washed before the analysis, 35.9 ng g m 1 were estimated. The higher amount of nicotine can be explained by the fact that tobacco smoke deposits were rinsed from the surface into the inner parts during the washing step. The results highlight the importance of additional analyses for metabolites; new patterns must be created that incorporate all now widespread drugs." @default.
- W2053847588 created "2016-06-24" @default.
- W2053847588 creator A5003879742 @default.
- W2053847588 creator A5006208281 @default.
- W2053847588 creator A5019658199 @default.
- W2053847588 creator A5078009536 @default.
- W2053847588 date "2002-01-01" @default.
- W2053847588 modified "2023-09-26" @default.
- W2053847588 title "Analysis of Nicotine in Archaeological Skeletons from the Early Modern Age and from the Bronze Age" @default.
- W2053847588 cites W1880163345 @default.
- W2053847588 cites W1973269259 @default.
- W2053847588 cites W2022899032 @default.
- W2053847588 cites W2036904810 @default.
- W2053847588 cites W2038848911 @default.
- W2053847588 cites W2042562574 @default.
- W2053847588 cites W2044833842 @default.
- W2053847588 cites W2064616699 @default.
- W2053847588 cites W2123280403 @default.
- W2053847588 cites W2147528426 @default.
- W2053847588 cites W2154694813 @default.
- W2053847588 cites W2156712567 @default.
- W2053847588 cites W2161421491 @default.
- W2053847588 doi "https://doi.org/10.1080/1358612021000010686" @default.
- W2053847588 hasPublicationYear "2002" @default.
- W2053847588 type Work @default.
- W2053847588 sameAs 2053847588 @default.
- W2053847588 citedByCount "21" @default.
- W2053847588 countsByYear W20538475882012 @default.
- W2053847588 countsByYear W20538475882013 @default.
- W2053847588 crossrefType "journal-article" @default.
- W2053847588 hasAuthorship W2053847588A5003879742 @default.
- W2053847588 hasAuthorship W2053847588A5006208281 @default.
- W2053847588 hasAuthorship W2053847588A5019658199 @default.
- W2053847588 hasAuthorship W2053847588A5078009536 @default.
- W2053847588 hasConcept C120876096 @default.
- W2053847588 hasConcept C126322002 @default.
- W2053847588 hasConcept C166957645 @default.
- W2053847588 hasConcept C205649164 @default.
- W2053847588 hasConcept C2776319443 @default.
- W2053847588 hasConcept C2777477808 @default.
- W2053847588 hasConcept C2778355491 @default.
- W2053847588 hasConcept C2779547902 @default.
- W2053847588 hasConcept C2908647359 @default.
- W2053847588 hasConcept C33070731 @default.
- W2053847588 hasConcept C71924100 @default.
- W2053847588 hasConcept C86803240 @default.
- W2053847588 hasConcept C99454951 @default.
- W2053847588 hasConceptScore W2053847588C120876096 @default.
- W2053847588 hasConceptScore W2053847588C126322002 @default.
- W2053847588 hasConceptScore W2053847588C166957645 @default.
- W2053847588 hasConceptScore W2053847588C205649164 @default.
- W2053847588 hasConceptScore W2053847588C2776319443 @default.
- W2053847588 hasConceptScore W2053847588C2777477808 @default.
- W2053847588 hasConceptScore W2053847588C2778355491 @default.
- W2053847588 hasConceptScore W2053847588C2779547902 @default.
- W2053847588 hasConceptScore W2053847588C2908647359 @default.
- W2053847588 hasConceptScore W2053847588C33070731 @default.
- W2053847588 hasConceptScore W2053847588C71924100 @default.
- W2053847588 hasConceptScore W2053847588C86803240 @default.
- W2053847588 hasConceptScore W2053847588C99454951 @default.
- W2053847588 hasIssue "2" @default.
- W2053847588 hasLocation W20538475881 @default.
- W2053847588 hasOpenAccess W2053847588 @default.
- W2053847588 hasPrimaryLocation W20538475881 @default.
- W2053847588 hasRelatedWork W1988146345 @default.
- W2053847588 hasRelatedWork W1997330015 @default.
- W2053847588 hasRelatedWork W2012692477 @default.
- W2053847588 hasRelatedWork W2040952485 @default.
- W2053847588 hasRelatedWork W2043719374 @default.
- W2053847588 hasRelatedWork W2064263789 @default.
- W2053847588 hasRelatedWork W2123583867 @default.
- W2053847588 hasRelatedWork W2157335019 @default.
- W2053847588 hasRelatedWork W2407536803 @default.
- W2053847588 hasRelatedWork W2409789723 @default.
- W2053847588 hasVolume "4" @default.
- W2053847588 isParatext "false" @default.
- W2053847588 isRetracted "false" @default.
- W2053847588 magId "2053847588" @default.
- W2053847588 workType "article" @default.