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- W205384865 abstract "So far, no consistent conclusions can be drawn regarding the acute effects of ethanol on receptor-stimulated phosphoinositide hydrolysis. Several authors have reported reduced formation of inositol phosphates (IP) in [3H]-labelled rat brain slices (3,6,7) but negative results have also been published (13). It seems that the choice of receptor and tissue to be studied is of importance for the final outcome of this type of investigation. Possibly, some of the inconsistencies can be explained by a selective sensitivity of the receptor agonists to ethanol. From the studies using brain-slice techniques, it is also difficult to establish which cell types are vulnerable to ethanol. Therefore, culturing primary cells or established cell-lines may serve as a useful tool for elucidating the complex mechanisms by which ethanol may exert its effects (see Alling et al. in this volume)." @default.
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- W205384865 date "1989-01-01" @default.
- W205384865 modified "2023-09-28" @default.
- W205384865 title "Ethanol and Bradykinin-Stimulated Phosphoinositide Hydrolysis in NG108–15 Neuroblastoma-Glioma Cells" @default.
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- W205384865 doi "https://doi.org/10.1007/978-1-4612-4514-8_15" @default.
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