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- W2053885685 abstract "<i>Background:</i> The wet-wrap dressing technique has proved to be beneficial in cases of exacerbated atopic dermatitis (AD) skin lesions. <i>Objective:</i> The effect of wet-wrap dressings was investigated in a controlled trial comparing a steroid (mometasone furoate 0.1%)-containing and a steroid-free (vehicle) preparation in an in-patient comparison study. <i>Methods:</i> 20 children aged 2–17 years with exacerbated AD were treated twice daily with wet-wrap dressings over a 5-day period. <i>Results:</i> AD in treated areas significantly improved in both study arms; however, the effect was significantly better in the mometasone-treated group (p < 0.01). Transepidermal water loss improved in both arms without any significant differences. <i>Staphylococcus aureus </i>colonization decreased during the first 3 days of active treatment independently of the therapeutic modalities chosen. At day 5, colony counts further dropped on the steroid-treated lesions. <i>Conclusion:</i> Application of the wet-wrap dressing technique for exacerbated AD lesions is effective, combination with a topical steroid being superior to a steroid-free application without bearing the risk of a bacterial superinfection." @default.
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- W2053885685 date "2002-01-01" @default.
- W2053885685 modified "2023-10-03" @default.
- W2053885685 title "Topical Steroids under Wet-Wrap Dressings in Atopic Dermatitis – A Vehicle-Controlled Trial" @default.
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- W2053885685 doi "https://doi.org/10.1159/000051811" @default.
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