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- W2053897009 abstract "This paper aims to study the abnormal patterns of brain glucose metabolism co-variations in Alzheimer disease (AD) and Mild Cognitive Impairment (MCI) patients compared to Normal healthy controls (NC) using the Alzheimer Disease Neuroimaging Initiative (ADNI) database. The local cerebral metabolic rate for glucose (CMRgl) in a set of 90 structures belonging to the AAL atlas was obtained from Fluro-Deoxyglucose Positron Emission Tomography data in resting state. It is assumed that brain regions whose CMRgl values are significantly correlated are functionally associated; therefore, when metabolism is altered in a single region, the alteration will affect the metabolism of other brain areas with which it interrelates. The glucose metabolism network (represented by the matrix of the CMRgl co-variations among all pairs of structures) was studied using the graph theory framework. The highest concurrent fluctuations in CMRgl were basically identified between homologous cortical regions in all groups. Significant differences in CMRgl co-variations in AD and MCI groups as compared to NC were found. The AD and MCI patients showed aberrant patterns in comparison to NC subjects, as detected by global and local network properties (global and local efficiency, clustering index, and others). MCI network's attributes showed an intermediate position between NC and AD, corroborating it as a transitional stage from normal aging to Alzheimer disease. Our study is an attempt at exploring the complex association between glucose metabolism, CMRgl covariations and the attributes of the brain network organization in AD and MCI." @default.
- W2053897009 created "2016-06-24" @default.
- W2053897009 creator A5061523263 @default.
- W2053897009 creator A5087318913 @default.
- W2053897009 creator A5089522677 @default.
- W2053897009 date "2013-07-23" @default.
- W2053897009 modified "2023-10-12" @default.
- W2053897009 title "Glucose Metabolism during Resting State Reveals Abnormal Brain Networks Organization in the Alzheimer’s Disease and Mild Cognitive Impairment" @default.
- W2053897009 cites W1522806115 @default.
- W2053897009 cites W1833717060 @default.
- W2053897009 cites W1847168837 @default.
- W2053897009 cites W1855610705 @default.
- W2053897009 cites W1929729372 @default.
- W2053897009 cites W1971937094 @default.
- W2053897009 cites W1972165090 @default.
- W2053897009 cites W1973612122 @default.
- W2053897009 cites W1974644418 @default.
- W2053897009 cites W1974764791 @default.
- W2053897009 cites W1976487116 @default.
- W2053897009 cites W1977087393 @default.
- W2053897009 cites W1979426401 @default.
- W2053897009 cites W1982974584 @default.
- W2053897009 cites W1983537704 @default.
- W2053897009 cites W1985659221 @default.
- W2053897009 cites W1987924998 @default.
- W2053897009 cites W1989128385 @default.
- W2053897009 cites W1991952617 @default.
- W2053897009 cites W1992037492 @default.
- W2053897009 cites W1994184572 @default.
- W2053897009 cites W1998791392 @default.
- W2053897009 cites W2002923643 @default.
- W2053897009 cites W2007572953 @default.
- W2053897009 cites W2008152557 @default.
- W2053897009 cites W2009360136 @default.
- W2053897009 cites W2010283825 @default.
- W2053897009 cites W2011541551 @default.
- W2053897009 cites W2012559638 @default.
- W2053897009 cites W2013930506 @default.
- W2053897009 cites W2014888437 @default.
- W2053897009 cites W2015259521 @default.
- W2053897009 cites W2016228161 @default.
- W2053897009 cites W2016635224 @default.
- W2053897009 cites W2020617938 @default.
- W2053897009 cites W2021954644 @default.
- W2053897009 cites W2022175261 @default.
- W2053897009 cites W2033242805 @default.
- W2053897009 cites W2034630192 @default.
- W2053897009 cites W2035507560 @default.
- W2053897009 cites W2037166045 @default.
- W2053897009 cites W2037704528 @default.
- W2053897009 cites W2043768383 @default.
- W2053897009 cites W2044356060 @default.
- W2053897009 cites W2044614452 @default.
- W2053897009 cites W2048207814 @default.
- W2053897009 cites W2050214509 @default.
- W2053897009 cites W2050852481 @default.
- W2053897009 cites W2051381776 @default.
- W2053897009 cites W2053082937 @default.
- W2053897009 cites W2055186021 @default.
- W2053897009 cites W2056647705 @default.
- W2053897009 cites W2058046532 @default.
- W2053897009 cites W2059776115 @default.
- W2053897009 cites W2060464767 @default.
- W2053897009 cites W2070722739 @default.
- W2053897009 cites W2072361983 @default.
- W2053897009 cites W2074925665 @default.
- W2053897009 cites W2075496760 @default.
- W2053897009 cites W2077383949 @default.
- W2053897009 cites W2078524519 @default.
- W2053897009 cites W2080816290 @default.
- W2053897009 cites W2081242195 @default.
- W2053897009 cites W2087938247 @default.
- W2053897009 cites W2089316130 @default.
- W2053897009 cites W2089691915 @default.
- W2053897009 cites W2090357978 @default.
- W2053897009 cites W2093972428 @default.
- W2053897009 cites W2096347759 @default.
- W2053897009 cites W2101670636 @default.
- W2053897009 cites W2104897414 @default.
- W2053897009 cites W2106905545 @default.
- W2053897009 cites W2107169104 @default.
- W2053897009 cites W2113075246 @default.
- W2053897009 cites W2113708991 @default.
- W2053897009 cites W2115017507 @default.
- W2053897009 cites W2116083905 @default.
- W2053897009 cites W2117995966 @default.
- W2053897009 cites W2118867177 @default.
- W2053897009 cites W2126650951 @default.
- W2053897009 cites W2129497119 @default.
- W2053897009 cites W2131328232 @default.
- W2053897009 cites W2133015986 @default.
- W2053897009 cites W2133259143 @default.
- W2053897009 cites W2133903921 @default.
- W2053897009 cites W2134858198 @default.
- W2053897009 cites W2135581837 @default.
- W2053897009 cites W2136435696 @default.
- W2053897009 cites W2138991775 @default.
- W2053897009 cites W2140348797 @default.