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- W2053934241 abstract "ABSTRACT In addition to life-threatening pneumonia, cytomegalovirus (CMV) may also causesubclinical pulmonary dysfunction after kidney transplantation. To investigate therole of plugging of cytomegalic endothelial cells (CEC) in the pulmonary capillarybed we prospectively determined specific carbon monoxide diffusion capacity(KCOc), and its components: the pulmonary diffusing membrane factor (Dm) andpulmonary capillary blood volume (Vcap) before and during CMV infection in 13kidney transplant recipients and 13 controls.During CMV infection median KCOc decreased significantly due to a decrease inboth Vcap and Dm. We illustrate the course of pulmonary diffusion in a male kidneytransplant recipient with CMV infection.We conclude that kidney transplant recipients with CMV infection have signi-ficant pulmonary diffusion disturbances due to a combination of lower Vcap andlower Dm. The most likely explanation for this phenomenon is a local inflammatoryprocess due to CMV and not plugging of cytomegalic endothelial cells." @default.
- W2053934241 created "2016-06-24" @default.
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- W2053934241 date "1999-02-01" @default.
- W2053934241 modified "2023-10-16" @default.
- W2053934241 title "Subclinical pneumonitis during cytomegalovirus infection after kidney transplantation" @default.
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- W2053934241 doi "https://doi.org/10.1016/s0041-1345(98)02038-7" @default.
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