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• W2053971811 abstract "The role of c-myc oncogene expression in myogenic differentiation has been established by transfecting rat myoblasts of the L6 cell line with plasmid pMT-myc, in which the c-myc coding sequences were under the control of the metallothionein I promoter. We observed that the constitutive expression of the exogenous c-myc gene inhibits muscular differentiation. A diminution of the endogenous c-myc gene expression occurs within the first 24 h after the transfer of the cells to a differentiating medium. This early decrease of c-myc expression is required for cell differentiation to occur. We have also observed that exogenous myc gene expression has no effect on endogenous myc expression." @default.
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• W2053971811 date "1987-09-01" @default.
• W2053971811 modified "2023-09-25" @default.
• W2053971811 title "c-myc Oncogene expression inhibits the initiation of myogenic differentiation" @default.
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• W2053971811 doi "https://doi.org/10.1016/0014-4827(87)90107-8" @default.
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