FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2054009455> ?p ?o ?g. }

• W2054009455 endingPage "314" @default.
• W2054009455 startingPage "307" @default.
• W2054009455 abstract "Prolactin-secreting pituitary adenomas may be managed by surgery, medication, radiotherapy, or observation. The authors reviewed a consecutive series of patients who were followed for at least 5 years after surgery to assess the prognostic significance of preoperative factors (tumor size and prolactin level) and an immediate postoperative factor (prolactin level obtained the morning after surgery) on long-term hormonal outcome, thereby clarifying the indications for surgical removal of tumor, the definition of successful treatment outcomes, and the nature of recurrent tumors.Between 1979 and 1991, 241 patients with prolactinomas underwent transsphenoidal resection. Nineteen patients were lost to follow-up review, whereas the remaining 222 patients underwent measurement of their prolactin levels on postoperative Day 1 (POD 1), at 6 and 12 weeks, and every 6 months thereafter for a minimum of 5 years. On POD 1, prolactin levels in 133 patients (Group 1) were lower than 10 ng/ml, in 43 patients (Group 2) between 10 and 20 ng/ml, and in 46 patients (Group 3) higher than 20 ng/ml. At 6 and 12 weeks, normal prolactin levels (< or = 20 ng/ml) were measured in 132 (99%) of the 133 patients in Group 1 but only in 32 (74%) of the 43 patients in Group 2. By 5 years postoperatively, normal levels of prolactin were still measured in 130 patients (98%) in Group 1 compared with only five patients (12%) in Group 2. No patient with a prolactin level lower than 3 ng/ml on POD 1 was found to have an elevated hormone level at 5 years. The likelihood of a long-term chemical cure was greater for patients with microadenomas (91% cure rate) than for those with macroadenomas (33%). Preoperative prolactin levels also correlated with hormonal outcome.Prolactin levels lower than 10 ng/ml on POD 1 predict a long-term chemical cure in patients with microadenomas (100% cure rate) and those with macroadenomas (93% cure rate). In contrast, a cure is not likely to be obtained in patients with normal levels ranging between 10 and 20 ng/ml on POD 1 if they harbor macroadenomas (0% cure rate). A recurrence reported several years after surgery probably represents the presence of persistent tumor that was not originally removed. If the initial operation was performed by an experienced surgeon, however, reoperation is not likely to yield a chemical cure." @default.
• W2054009455 created "2016-06-24" @default.
• W2054009455 creator A5003958184 @default.
• W2054009455 creator A5005432869 @default.
• W2054009455 creator A5060324899 @default.
• W2054009455 creator A5066434631 @default.
• W2054009455 date "2002-08-01" @default.
• W2054009455 modified "2023-10-16" @default.
• W2054009455 title "Predictive value of serum prolactin levels measured immediately after transsphenoidal surgery" @default.
• W2054009455 cites W1506842957 @default.
• W2054009455 cites W1686642321 @default.
• W2054009455 cites W1965908443 @default.
• W2054009455 cites W1968674415 @default.
• W2054009455 cites W1977942434 @default.
• W2054009455 cites W1990716944 @default.
• W2054009455 cites W1991347827 @default.
• W2054009455 cites W1994368364 @default.
• W2054009455 cites W1998903561 @default.
• W2054009455 cites W2000831607 @default.
• W2054009455 cites W2002308074 @default.
• W2054009455 cites W2003639484 @default.
• W2054009455 cites W2004643337 @default.
• W2054009455 cites W2006684700 @default.
• W2054009455 cites W2011846252 @default.
• W2054009455 cites W2013558859 @default.
• W2054009455 cites W2022840294 @default.
• W2054009455 cites W2030548613 @default.
• W2054009455 cites W2040892630 @default.
• W2054009455 cites W2045980226 @default.
• W2054009455 cites W2047557211 @default.
• W2054009455 cites W2049486103 @default.
• W2054009455 cites W2054425062 @default.
• W2054009455 cites W2054901059 @default.
• W2054009455 cites W2057971885 @default.
• W2054009455 cites W2062071496 @default.
• W2054009455 cites W2073759840 @default.
• W2054009455 cites W2087438035 @default.
• W2054009455 cites W2089428133 @default.
• W2054009455 cites W2091336801 @default.
• W2054009455 cites W2091710956 @default.
• W2054009455 cites W2092759803 @default.
• W2054009455 cites W2094174325 @default.
• W2054009455 cites W2100843929 @default.
• W2054009455 cites W2109637259 @default.
• W2054009455 cites W2145367758 @default.
• W2054009455 cites W2153683302 @default.
• W2054009455 cites W2165368949 @default.
• W2054009455 cites W2327589817 @default.
• W2054009455 cites W2339977047 @default.
• W2054009455 cites W2412716308 @default.
• W2054009455 cites W2419377929 @default.
• W2054009455 cites W40593796 @default.
• W2054009455 cites W4211056031 @default.
• W2054009455 cites W4211195992 @default.
• W2054009455 cites W4236514138 @default.
• W2054009455 cites W4296086231 @default.
• W2054009455 cites W67797838 @default.
• W2054009455 doi "https://doi.org/10.3171/jns.2002.97.2.0307" @default.
• W2054009455 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12186458" @default.
• W2054009455 hasPublicationYear "2002" @default.
• W2054009455 type Work @default.
• W2054009455 sameAs 2054009455 @default.
• W2054009455 citedByCount "98" @default.
• W2054009455 countsByYear W20540094552012 @default.
• W2054009455 countsByYear W20540094552013 @default.
• W2054009455 countsByYear W20540094552014 @default.
• W2054009455 countsByYear W20540094552015 @default.
• W2054009455 countsByYear W20540094552016 @default.
• W2054009455 countsByYear W20540094552017 @default.
• W2054009455 countsByYear W20540094552018 @default.
• W2054009455 countsByYear W20540094552019 @default.
• W2054009455 countsByYear W20540094552020 @default.
• W2054009455 countsByYear W20540094552021 @default.
• W2054009455 countsByYear W20540094552022 @default.
• W2054009455 countsByYear W20540094552023 @default.
• W2054009455 crossrefType "journal-article" @default.
• W2054009455 hasAuthorship W2054009455A5003958184 @default.
• W2054009455 hasAuthorship W2054009455A5005432869 @default.
• W2054009455 hasAuthorship W2054009455A5060324899 @default.
• W2054009455 hasAuthorship W2054009455A5066434631 @default.
• W2054009455 hasConcept C126322002 @default.
• W2054009455 hasConcept C141071460 @default.
• W2054009455 hasConcept C19720800 @default.
• W2054009455 hasConcept C2777428134 @default.
• W2054009455 hasConcept C2777658017 @default.
• W2054009455 hasConcept C2779064019 @default.
• W2054009455 hasConcept C2779318953 @default.
• W2054009455 hasConcept C2779653919 @default.
• W2054009455 hasConcept C2781449511 @default.
• W2054009455 hasConcept C2908910360 @default.
• W2054009455 hasConcept C71315377 @default.
• W2054009455 hasConcept C71924100 @default.
• W2054009455 hasConceptScore W2054009455C126322002 @default.
• W2054009455 hasConceptScore W2054009455C141071460 @default.
• W2054009455 hasConceptScore W2054009455C19720800 @default.
• W2054009455 hasConceptScore W2054009455C2777428134 @default.
• W2054009455 hasConceptScore W2054009455C2777658017 @default.
• W2054009455 hasConceptScore W2054009455C2779064019 @default.

• next