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- W2054054718 abstract "Compound auditory nerve action potentials (APs) and cochlear microphonics (CMs) were recorded from the round-window of kittens aged 3–9 weeks and of adult cats. Animals were anaesthetized and pure tone stimuli were delivered via calibrated, sealed, transducer systems. AP and CM amplitude and AP latency were measured over a wide range of stimulus intensities (up to 80 dB SPL) and at 5 octave-interval stimulus frequencis (1–16 kHz). At low stimulus intensity levels, AP amplitude hadattained adult levels to low and high frequency stimuli by 6/12 weeks of age to mid-frequency stimuli by 9 weeks. As stimulus intensity levels were increased, the kitten input-output functions diverged progressively from those of the adults. At these higher intensity levels, AP amplitude maturation in even the 9 week animals was incomplete. AP latencies to stimuli of all frequencies shortened between the third and fourth weeks but remained stable thereafter. CM amplitude also reached maturity by the fourth week. These findings suggest that the development of AP after the fourth week consists of an increase in the synchrony of auditory nerve fibre responses, since both the fine structure of the cochlea and the responses of single nerve fibres are known to be mature by the end of the first postnatal month." @default.
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- W2054054718 date "1981-08-01" @default.
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- W2054054718 title "Development of the cat peripheral auditory system: input-output functions of cochlear potentials" @default.
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- W2054054718 doi "https://doi.org/10.1016/0006-8993(81)90265-1" @default.
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