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• W2054100548 abstract "<b>Background:</b> Central nervous system fungal infections (FI) are important complications and a cause of mortality in patients who receive hematopoietic stem cell transplantation (HSCT). <b>Aims:</b> To study the clinical aspects of fungal encephalitis (FE). <b>Settings and Design:</b> The study was carried out at the HSCT Center of the Hospital de Clνnicas, Federal University of Paranα, Curitiba, Brazil. <b>Materials and Methods:</b> Clinical records and autopsy reports from patients submitted to HSCT with a diagnosis of FE. <b>Results:</b> Twelve patients were diagnosed with FE presenting with lowered level of consciousness, hemiparesis and seizures. We were able to identify two subgroups regarding susceptibility to FE: (1) patients with early onset FI and severe leucopoenia, and (2) patients with later onset FI with graft-versus-host disease using immunosuppressive drugs. Eleven of the patients died directly due to the neurological complication, all had post-mortem confirmation of the diagnosis of FI. <b>Conclusions:</b> These clinical, paraclinical and temporal patterns may provide the opportunity for earlier diagnosis and interventions." @default.
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• W2054100548 date "2008-01-01" @default.
• W2054100548 modified "2023-10-12" @default.
• W2054100548 title "Fungal encephalitis following bone marrow transplantation: Clinical findings and prognosis" @default.
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• W2054100548 doi "https://doi.org/10.4103/0022-3859.41802" @default.
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