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• W2054112855 abstract "Summary Approximately 15% of patients with ulcerative colitis have a severe attack requiring hospitalization at some time during their illness. This treatment leads to a remission in 60–80% of patients and non‐responders may require a total colectomy. Mortality in severe episodes of ulcerative colitis decreased from 31–61% in the 1950s to 5–9% in the 1960s thanks to the introduction of steroids and to a policy of early colectomy. Recently, some new drugs have been shown to be effective in the treatment of severe steroid‐refractory ulcerative colitis. This review concentrates on the clinical evaluation, prognostic factors and new developments in medical therapy in severe ulcerative colitis. A retrospective evaluation of a consecutive series of patients with severe ulcerative colitis admitted to a Gastroenterology Department in Torino, Italy, is also reported." @default.
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• W2054112855 date "2002-05-31" @default.
• W2054112855 modified "2023-09-27" @default.
• W2054112855 title "Medical treatment of severe ulcerative colitis" @default.
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• W2054112855 doi "https://doi.org/10.1046/j.1365-2036.16.s4.2.x" @default.
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