FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2054163031> ?p ?o ?g. }

• W2054163031 endingPage "204" @default.
• W2054163031 startingPage "197" @default.
• W2054163031 abstract "Dopamine receptor modulation of noradrenaline release from renal sympathetic nerves was investigated. Human kidney slices were incubated with 3H-noradrenaline, placed into superfusion chambers between two platinum electrodes and field-stimulated at 5 Hz. The slices accumulated radioactivity. Pretreatment of the kidney slices with 6-hydroxy-dopamine (1.2 mM) prior to the 3H-noradrenaline incubation reduced the accumulation of radioactivity. The stimulation induced (S-I) outflow of radioactivity was mainly composed of intact 3H-noradrenaline. The sodium channel blocker tetrodotoxin (1 microM), 6-hydroxy-dopamine pretreatment and omission of calcium from the superfusion solution abolished S-I outflow of radioactivity. The DA1-receptor agonist fenoldopam (SKF 82526; 0.01 and 0.1 microM) did not alter but fenoldopam (1 microM) increased S-I outflow of radioactivity. However, in the presence of either the non-selective alpha-adrenoceptor antagonist phentolamine (1 microM) or the selective alpha 2-adrenoceptor antagonist idazoxan (1 microM) fenoldopam (1 microM) had no effect. The DA2-receptor agonist quinpirole (LY 171555; 1 microM) inhibited S-I outflow of radioactivity, an effect blocked by the selective DA2-receptor antagonists S(-)-sulpiride (10 microM) and domperidone (0.3 microM) but unaltered either by the DA1-receptor antagonist SCH 23390 (1 microM) or by phentolamine (1 microM). The alpha 2-adrenoceptor agonist UK 14304 (0.1 microM) inhibited S-I outflow of radioactivity, and this effect was blocked by phentolamine (1 microM) and idazoxan (1 microM) but unaltered by S(-)-sulpiride (10 microM). Phentolamine and idazoxan, in contrast to S(-)-sulpiride, domperidone and SCH 23390, enhanced S-I outflow of radioactivity by themselves.(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
• W2054163031 created "2016-06-24" @default.
• W2054163031 creator A5042974205 @default.
• W2054163031 creator A5047849164 @default.
• W2054163031 creator A5050154759 @default.
• W2054163031 creator A5057230580 @default.
• W2054163031 creator A5077391770 @default.
• W2054163031 creator A5078764308 @default.
• W2054163031 date "1993-01-01" @default.
• W2054163031 modified "2023-10-15" @default.
• W2054163031 title "Dopamine DA2-receptor activation inhibits noradrenaline release in human kidney slices" @default.
• W2054163031 cites W12984134 @default.
• W2054163031 cites W1488521817 @default.
• W2054163031 cites W1518247835 @default.
• W2054163031 cites W1970592744 @default.
• W2054163031 cites W1973236311 @default.
• W2054163031 cites W1974959837 @default.
• W2054163031 cites W1977350550 @default.
• W2054163031 cites W1979908776 @default.
• W2054163031 cites W1982211166 @default.
• W2054163031 cites W1982469569 @default.
• W2054163031 cites W1984201605 @default.
• W2054163031 cites W1986630042 @default.
• W2054163031 cites W1991756562 @default.
• W2054163031 cites W2003481821 @default.
• W2054163031 cites W2027083829 @default.
• W2054163031 cites W2029712303 @default.
• W2054163031 cites W2030668059 @default.
• W2054163031 cites W2037703041 @default.
• W2054163031 cites W2046109734 @default.
• W2054163031 cites W2053125298 @default.
• W2054163031 cites W2056713336 @default.
• W2054163031 cites W2058541924 @default.
• W2054163031 cites W2061904925 @default.
• W2054163031 cites W2062914145 @default.
• W2054163031 cites W2079512972 @default.
• W2054163031 cites W2081059429 @default.
• W2054163031 cites W2081150074 @default.
• W2054163031 cites W2094119110 @default.
• W2054163031 cites W2105793308 @default.
• W2054163031 cites W2112735576 @default.
• W2054163031 cites W2139446059 @default.
• W2054163031 cites W2142821028 @default.
• W2054163031 cites W2462910056 @default.
• W2054163031 cites W4241324481 @default.
• W2054163031 cites W72363943 @default.
• W2054163031 cites W1976011841 @default.
• W2054163031 doi "https://doi.org/10.1038/ki.1993.32" @default.
• W2054163031 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8094472" @default.
• W2054163031 hasPublicationYear "1993" @default.
• W2054163031 type Work @default.
• W2054163031 sameAs 2054163031 @default.
• W2054163031 citedByCount "45" @default.
• W2054163031 countsByYear W20541630312013 @default.
• W2054163031 countsByYear W20541630312017 @default.
• W2054163031 countsByYear W20541630312022 @default.
• W2054163031 crossrefType "journal-article" @default.
• W2054163031 hasAuthorship W2054163031A5042974205 @default.
• W2054163031 hasAuthorship W2054163031A5047849164 @default.
• W2054163031 hasAuthorship W2054163031A5050154759 @default.
• W2054163031 hasAuthorship W2054163031A5057230580 @default.
• W2054163031 hasAuthorship W2054163031A5077391770 @default.
• W2054163031 hasAuthorship W2054163031A5078764308 @default.
• W2054163031 hasBestOaLocation W20541630311 @default.
• W2054163031 hasConcept C120069818 @default.
• W2054163031 hasConcept C126322002 @default.
• W2054163031 hasConcept C134018914 @default.
• W2054163031 hasConcept C170493617 @default.
• W2054163031 hasConcept C185592680 @default.
• W2054163031 hasConcept C24998067 @default.
• W2054163031 hasConcept C2776885963 @default.
• W2054163031 hasConcept C2778296116 @default.
• W2054163031 hasConcept C2778938600 @default.
• W2054163031 hasConcept C2779867896 @default.
• W2054163031 hasConcept C2779917531 @default.
• W2054163031 hasConcept C2780253649 @default.
• W2054163031 hasConcept C2780648677 @default.
• W2054163031 hasConcept C2780806966 @default.
• W2054163031 hasConcept C2780939551 @default.
• W2054163031 hasConcept C513476851 @default.
• W2054163031 hasConcept C71924100 @default.
• W2054163031 hasConcept C86803240 @default.
• W2054163031 hasConceptScore W2054163031C120069818 @default.
• W2054163031 hasConceptScore W2054163031C126322002 @default.
• W2054163031 hasConceptScore W2054163031C134018914 @default.
• W2054163031 hasConceptScore W2054163031C170493617 @default.
• W2054163031 hasConceptScore W2054163031C185592680 @default.
• W2054163031 hasConceptScore W2054163031C24998067 @default.
• W2054163031 hasConceptScore W2054163031C2776885963 @default.
• W2054163031 hasConceptScore W2054163031C2778296116 @default.
• W2054163031 hasConceptScore W2054163031C2778938600 @default.
• W2054163031 hasConceptScore W2054163031C2779867896 @default.
• W2054163031 hasConceptScore W2054163031C2779917531 @default.
• W2054163031 hasConceptScore W2054163031C2780253649 @default.
• W2054163031 hasConceptScore W2054163031C2780648677 @default.
• W2054163031 hasConceptScore W2054163031C2780806966 @default.
• W2054163031 hasConceptScore W2054163031C2780939551 @default.
• W2054163031 hasConceptScore W2054163031C513476851 @default.

• next