Matches in SemOpenAlex for { <https://semopenalex.org/work/W2054173655> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2054173655 endingPage "659" @default.
- W2054173655 startingPage "653" @default.
- W2054173655 abstract "The induction of Rb gene expression is a key event in the process of myogenic differentiation. We recently demonstrated that transcription of the Rb gene is repressed by MIZF, previously characterized as an MBD2-binding partner. Here we show the new roles of MIZF as a regulator of myogenic differentiation. MIZF mRNA was detected in undifferentiated C2C12 myoblasts but its expression decreased during myogenesis, correlating with an increase in Rb mRNA. To examine the function of MIZF in regulating myogenic differentiation, we transduced C2C12 myoblasts with adenoviral vectors to constitutively produce MIZF at high levels. When switched to differentiation medium, these cells showed decreased expression of Rb as well as differentiation markers such as myogenin and Troponin-T, and consequently could not differentiate into multinucleated myotubes. These results suggest that transcriptional repression of Rb by MIZF could be one of the critical determinants in myogenic differentiation." @default.
- W2054173655 created "2016-06-24" @default.
- W2054173655 creator A5053895726 @default.
- W2054173655 creator A5064428590 @default.
- W2054173655 date "2004-12-01" @default.
- W2054173655 modified "2023-09-25" @default.
- W2054173655 title "Regulation of Rb gene expression by an MBD2-interacting zinc finger protein MIZF during myogenic differentiation" @default.
- W2054173655 cites W1486257535 @default.
- W2054173655 cites W1567517848 @default.
- W2054173655 cites W1616174717 @default.
- W2054173655 cites W1637312052 @default.
- W2054173655 cites W1784857457 @default.
- W2054173655 cites W178589356 @default.
- W2054173655 cites W1999330214 @default.
- W2054173655 cites W2014817033 @default.
- W2054173655 cites W2045718661 @default.
- W2054173655 cites W2051541258 @default.
- W2054173655 cites W2059577313 @default.
- W2054173655 cites W2084101481 @default.
- W2054173655 cites W2115147255 @default.
- W2054173655 cites W2121628947 @default.
- W2054173655 cites W2135944212 @default.
- W2054173655 cites W2137546188 @default.
- W2054173655 cites W2153900602 @default.
- W2054173655 cites W2166300250 @default.
- W2054173655 cites W2168401498 @default.
- W2054173655 cites W2061076014 @default.
- W2054173655 doi "https://doi.org/10.1016/j.bbrc.2004.10.090" @default.
- W2054173655 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15541338" @default.
- W2054173655 hasPublicationYear "2004" @default.
- W2054173655 type Work @default.
- W2054173655 sameAs 2054173655 @default.
- W2054173655 citedByCount "7" @default.
- W2054173655 countsByYear W20541736552017 @default.
- W2054173655 countsByYear W20541736552018 @default.
- W2054173655 countsByYear W20541736552023 @default.
- W2054173655 crossrefType "journal-article" @default.
- W2054173655 hasAuthorship W2054173655A5053895726 @default.
- W2054173655 hasAuthorship W2054173655A5064428590 @default.
- W2054173655 hasConcept C104317684 @default.
- W2054173655 hasConcept C136403682 @default.
- W2054173655 hasConcept C148738053 @default.
- W2054173655 hasConcept C150194340 @default.
- W2054173655 hasConcept C153911025 @default.
- W2054173655 hasConcept C165864922 @default.
- W2054173655 hasConcept C186310378 @default.
- W2054173655 hasConcept C207200792 @default.
- W2054173655 hasConcept C2778106681 @default.
- W2054173655 hasConcept C2780508455 @default.
- W2054173655 hasConcept C3763915 @default.
- W2054173655 hasConcept C54355233 @default.
- W2054173655 hasConcept C60278653 @default.
- W2054173655 hasConcept C86339819 @default.
- W2054173655 hasConcept C86803240 @default.
- W2054173655 hasConcept C95444343 @default.
- W2054173655 hasConcept C97816823 @default.
- W2054173655 hasConceptScore W2054173655C104317684 @default.
- W2054173655 hasConceptScore W2054173655C136403682 @default.
- W2054173655 hasConceptScore W2054173655C148738053 @default.
- W2054173655 hasConceptScore W2054173655C150194340 @default.
- W2054173655 hasConceptScore W2054173655C153911025 @default.
- W2054173655 hasConceptScore W2054173655C165864922 @default.
- W2054173655 hasConceptScore W2054173655C186310378 @default.
- W2054173655 hasConceptScore W2054173655C207200792 @default.
- W2054173655 hasConceptScore W2054173655C2778106681 @default.
- W2054173655 hasConceptScore W2054173655C2780508455 @default.
- W2054173655 hasConceptScore W2054173655C3763915 @default.
- W2054173655 hasConceptScore W2054173655C54355233 @default.
- W2054173655 hasConceptScore W2054173655C60278653 @default.
- W2054173655 hasConceptScore W2054173655C86339819 @default.
- W2054173655 hasConceptScore W2054173655C86803240 @default.
- W2054173655 hasConceptScore W2054173655C95444343 @default.
- W2054173655 hasConceptScore W2054173655C97816823 @default.
- W2054173655 hasIssue "3" @default.
- W2054173655 hasLocation W20541736551 @default.
- W2054173655 hasLocation W20541736552 @default.
- W2054173655 hasOpenAccess W2054173655 @default.
- W2054173655 hasPrimaryLocation W20541736551 @default.
- W2054173655 hasRelatedWork W1973032259 @default.
- W2054173655 hasRelatedWork W1976822897 @default.
- W2054173655 hasRelatedWork W2001889965 @default.
- W2054173655 hasRelatedWork W2054173655 @default.
- W2054173655 hasRelatedWork W2072307284 @default.
- W2054173655 hasRelatedWork W2591884337 @default.
- W2054173655 hasRelatedWork W2735505291 @default.
- W2054173655 hasRelatedWork W2935800686 @default.
- W2054173655 hasRelatedWork W2987022347 @default.
- W2054173655 hasRelatedWork W3158159552 @default.
- W2054173655 hasVolume "325" @default.
- W2054173655 isParatext "false" @default.
- W2054173655 isRetracted "false" @default.
- W2054173655 magId "2054173655" @default.
- W2054173655 workType "article" @default.