Matches in SemOpenAlex for { <https://semopenalex.org/work/W2054178434> ?p ?o ?g. }
- W2054178434 endingPage "353" @default.
- W2054178434 startingPage "343" @default.
- W2054178434 abstract "Respiratory viral infections trigger a robust inflammatory response in the lung, producing cytokines, chemokines, and growth factors that promote infiltration of effector leukocytes. Whereas the role of chemokines and infiltrating leukocytes in antiviral immunity is well studied, the effect that lung cytokines have on leukocytes in distal hematopoietic and lymphoid tissues and their role in antiviral immunity is unknown. We show that, during infection with influenza or Sendai virus, the lung communicates with the sterile bone marrow, the primary site of hematopoiesis, through type I interferons. While in the bone marrow, leukocytes exposed to type I interferons activate an antiviral transcriptional program and become resistant to infection with different viruses. The protected bone marrow leukocytes are capable of migrating to the infected lung and contribute to virus clearance. These findings show that appropriate instruction of cells during their development in the bone marrow is needed for effective control of infection." @default.
- W2054178434 created "2016-06-24" @default.
- W2054178434 creator A5058399472 @default.
- W2054178434 creator A5077956716 @default.
- W2054178434 creator A5079116607 @default.
- W2054178434 creator A5090326690 @default.
- W2054178434 date "2010-05-01" @default.
- W2054178434 modified "2023-10-18" @default.
- W2054178434 title "Antiviral Instruction of Bone Marrow Leukocytes during Respiratory Viral Infections" @default.
- W2054178434 cites W1483855356 @default.
- W2054178434 cites W1524365680 @default.
- W2054178434 cites W1631977896 @default.
- W2054178434 cites W1667435701 @default.
- W2054178434 cites W1915328179 @default.
- W2054178434 cites W1967100189 @default.
- W2054178434 cites W1976006181 @default.
- W2054178434 cites W1977142289 @default.
- W2054178434 cites W1993547722 @default.
- W2054178434 cites W2000393599 @default.
- W2054178434 cites W2000844825 @default.
- W2054178434 cites W2008727517 @default.
- W2054178434 cites W2010472544 @default.
- W2054178434 cites W2011059916 @default.
- W2054178434 cites W2015785347 @default.
- W2054178434 cites W2017439081 @default.
- W2054178434 cites W2021821241 @default.
- W2054178434 cites W2034866046 @default.
- W2054178434 cites W2038474674 @default.
- W2054178434 cites W2038970416 @default.
- W2054178434 cites W2043851305 @default.
- W2054178434 cites W2045000380 @default.
- W2054178434 cites W2052904272 @default.
- W2054178434 cites W2067269714 @default.
- W2054178434 cites W2079090941 @default.
- W2054178434 cites W2080658428 @default.
- W2054178434 cites W2086310342 @default.
- W2054178434 cites W2087143957 @default.
- W2054178434 cites W2092715704 @default.
- W2054178434 cites W2096372976 @default.
- W2054178434 cites W2097289788 @default.
- W2054178434 cites W2099019634 @default.
- W2054178434 cites W2099926545 @default.
- W2054178434 cites W2101526959 @default.
- W2054178434 cites W2103054294 @default.
- W2054178434 cites W2103069849 @default.
- W2054178434 cites W2112284938 @default.
- W2054178434 cites W2114913546 @default.
- W2054178434 cites W2116562412 @default.
- W2054178434 cites W2117515288 @default.
- W2054178434 cites W2131815101 @default.
- W2054178434 cites W2133793569 @default.
- W2054178434 cites W2135703618 @default.
- W2054178434 cites W2141186997 @default.
- W2054178434 cites W2148148250 @default.
- W2054178434 cites W2150098469 @default.
- W2054178434 cites W2159470225 @default.
- W2054178434 cites W2160063406 @default.
- W2054178434 cites W2162250600 @default.
- W2054178434 cites W2164150624 @default.
- W2054178434 cites W2164743819 @default.
- W2054178434 doi "https://doi.org/10.1016/j.chom.2010.04.006" @default.
- W2054178434 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2874206" @default.
- W2054178434 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20478536" @default.
- W2054178434 hasPublicationYear "2010" @default.
- W2054178434 type Work @default.
- W2054178434 sameAs 2054178434 @default.
- W2054178434 citedByCount "66" @default.
- W2054178434 countsByYear W20541784342012 @default.
- W2054178434 countsByYear W20541784342013 @default.
- W2054178434 countsByYear W20541784342014 @default.
- W2054178434 countsByYear W20541784342015 @default.
- W2054178434 countsByYear W20541784342016 @default.
- W2054178434 countsByYear W20541784342017 @default.
- W2054178434 countsByYear W20541784342018 @default.
- W2054178434 countsByYear W20541784342019 @default.
- W2054178434 countsByYear W20541784342020 @default.
- W2054178434 countsByYear W20541784342021 @default.
- W2054178434 countsByYear W20541784342022 @default.
- W2054178434 countsByYear W20541784342023 @default.
- W2054178434 crossrefType "journal-article" @default.
- W2054178434 hasAuthorship W2054178434A5058399472 @default.
- W2054178434 hasAuthorship W2054178434A5077956716 @default.
- W2054178434 hasAuthorship W2054178434A5079116607 @default.
- W2054178434 hasAuthorship W2054178434A5090326690 @default.
- W2054178434 hasBestOaLocation W20541784341 @default.
- W2054178434 hasConcept C105702510 @default.
- W2054178434 hasConcept C109159458 @default.
- W2054178434 hasConcept C126322002 @default.
- W2054178434 hasConcept C13373296 @default.
- W2054178434 hasConcept C159047783 @default.
- W2054178434 hasConcept C203014093 @default.
- W2054178434 hasConcept C2522874641 @default.
- W2054178434 hasConcept C2776914184 @default.
- W2054178434 hasConcept C2777714996 @default.
- W2054178434 hasConcept C2779341262 @default.
- W2054178434 hasConcept C2780007613 @default.
- W2054178434 hasConcept C2780127873 @default.
- W2054178434 hasConcept C28328180 @default.