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- W2054186013 abstract "Werner's syndrome is a rare disease of premature ageing. The WRN gene product defective in this disorder belongs to the RecQ helicase family and is thought to be involved in DNA metabolism. Another protein, which plays an important role in both DNA replication and repair, is the poly‐ADP ribosyl transferase. Here we demonstrate an interaction of these two proteins resulting in ADP‐ribosylation of the WRN protein. These results imply that WRN is involved in DNA replication and in DNA repair." @default.
- W2054186013 created "2016-06-24" @default.
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- W2054186013 date "2003-10-03" @default.
- W2054186013 modified "2023-10-14" @default.
- W2054186013 title "Physical and functional interaction of the Werner syndrome protein with poly-ADP ribosyl transferase" @default.
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- W2054186013 doi "https://doi.org/10.1016/s0014-5793(03)01088-3" @default.
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