Matches in SemOpenAlex for { <https://semopenalex.org/work/W2054236369> ?p ?o ?g. }
- W2054236369 endingPage "711" @default.
- W2054236369 startingPage "706" @default.
- W2054236369 abstract "Long interspersed element-1 (LINE-1, or L1) is a non-long terminal repeat (LTR) retrotransposon that has amplified to hundreds of thousands of copies in mammalian evolution. A small number of the individual copies of L1 are active retrotransposons which are presently replicating in most species, including humans and mice. L1 retrotransposition begins with transcription of an active element and ends with a newly inserted cDNA copy, a process which requires the two element-encoded proteins to act in cis on the L1 RNA. The ORF1 protein (ORF1p) is a high-affinity, non-sequence-specific RNA binding protein with nucleic acid chaperone activity, whereas the ORF2 protein (ORF2p) supplies the enzymatic activities for cDNA synthesis. This article reviews the nucleic acid chaperone properties of ORF1p in the context of L1 retrotransposition." @default.
- W2054236369 created "2016-06-24" @default.
- W2054236369 creator A5071390116 @default.
- W2054236369 date "2010-11-01" @default.
- W2054236369 modified "2023-10-17" @default.
- W2054236369 title "Nucleic acid chaperone properties of ORF1p from the non-LTR retrotransposon, LINE-1" @default.
- W2054236369 cites W1509378838 @default.
- W2054236369 cites W1641947900 @default.
- W2054236369 cites W166408772 @default.
- W2054236369 cites W1965141089 @default.
- W2054236369 cites W1967352352 @default.
- W2054236369 cites W1976011820 @default.
- W2054236369 cites W1981932058 @default.
- W2054236369 cites W1985582783 @default.
- W2054236369 cites W1988495745 @default.
- W2054236369 cites W1989947837 @default.
- W2054236369 cites W1991333931 @default.
- W2054236369 cites W1997873146 @default.
- W2054236369 cites W1998983269 @default.
- W2054236369 cites W1999494370 @default.
- W2054236369 cites W2001806616 @default.
- W2054236369 cites W2005361700 @default.
- W2054236369 cites W2007589425 @default.
- W2054236369 cites W2024364777 @default.
- W2054236369 cites W2024654096 @default.
- W2054236369 cites W2032669220 @default.
- W2054236369 cites W2036994672 @default.
- W2054236369 cites W2039663986 @default.
- W2054236369 cites W2041074982 @default.
- W2054236369 cites W2041152528 @default.
- W2054236369 cites W2041516645 @default.
- W2054236369 cites W2043710895 @default.
- W2054236369 cites W2044073797 @default.
- W2054236369 cites W2051443579 @default.
- W2054236369 cites W2051541780 @default.
- W2054236369 cites W2064629259 @default.
- W2054236369 cites W2068584800 @default.
- W2054236369 cites W2071660897 @default.
- W2054236369 cites W2081293476 @default.
- W2054236369 cites W2086739233 @default.
- W2054236369 cites W2087231400 @default.
- W2054236369 cites W2088186616 @default.
- W2054236369 cites W2089471275 @default.
- W2054236369 cites W2093606206 @default.
- W2054236369 cites W2102773855 @default.
- W2054236369 cites W2106635550 @default.
- W2054236369 cites W2113973815 @default.
- W2054236369 cites W2114766453 @default.
- W2054236369 cites W2119390857 @default.
- W2054236369 cites W2120041527 @default.
- W2054236369 cites W2121584886 @default.
- W2054236369 cites W2124036670 @default.
- W2054236369 cites W2125750485 @default.
- W2054236369 cites W2127756769 @default.
- W2054236369 cites W2128777141 @default.
- W2054236369 cites W2140174097 @default.
- W2054236369 cites W2146078671 @default.
- W2054236369 cites W2149180811 @default.
- W2054236369 cites W2150800455 @default.
- W2054236369 cites W2151464048 @default.
- W2054236369 cites W2152161577 @default.
- W2054236369 cites W2155550415 @default.
- W2054236369 cites W2158444660 @default.
- W2054236369 cites W2163157311 @default.
- W2054236369 cites W2168909179 @default.
- W2054236369 cites W2169702991 @default.
- W2054236369 cites W2171976338 @default.
- W2054236369 doi "https://doi.org/10.4161/rna.7.6.13766" @default.
- W2054236369 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3073329" @default.
- W2054236369 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21045547" @default.
- W2054236369 hasPublicationYear "2010" @default.
- W2054236369 type Work @default.
- W2054236369 sameAs 2054236369 @default.
- W2054236369 citedByCount "78" @default.
- W2054236369 countsByYear W20542363692012 @default.
- W2054236369 countsByYear W20542363692013 @default.
- W2054236369 countsByYear W20542363692014 @default.
- W2054236369 countsByYear W20542363692015 @default.
- W2054236369 countsByYear W20542363692016 @default.
- W2054236369 countsByYear W20542363692017 @default.
- W2054236369 countsByYear W20542363692018 @default.
- W2054236369 countsByYear W20542363692019 @default.
- W2054236369 countsByYear W20542363692020 @default.
- W2054236369 countsByYear W20542363692021 @default.
- W2054236369 countsByYear W20542363692022 @default.
- W2054236369 countsByYear W20542363692023 @default.
- W2054236369 crossrefType "journal-article" @default.
- W2054236369 hasAuthorship W2054236369A5071390116 @default.
- W2054236369 hasBestOaLocation W20542363691 @default.
- W2054236369 hasConcept C104317684 @default.
- W2054236369 hasConcept C138885662 @default.
- W2054236369 hasConcept C141231307 @default.
- W2054236369 hasConcept C142724271 @default.
- W2054236369 hasConcept C150194340 @default.
- W2054236369 hasConcept C153911025 @default.
- W2054236369 hasConcept C179926584 @default.
- W2054236369 hasConcept C187882448 @default.
- W2054236369 hasConcept C199491388 @default.