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- W2054248997 abstract "Objective: To evaluate the significance of two-color interphase fluorescence in situ hybridization (FISH) using X and Y centromere probe in the engraftment estimation and minimal residual disease (MRD) monitoring after allogeneic stem cell transplantation (alloSCT). Methods: Samples from 12 cases patients in different periods after alloSCT were detected by interphase FISH. Results: All of the 12 patients were proved to obtain engraftment 22–35 days after alloSCT. While traditional karyotype showed as 100%XX or 100%XY invariably, FISH showed different percentages of donor original sex chromosome. Conclusion: Two-color interphase FISH is a more sensitive and simple test for engraftment evaluation and MRD monitoring post SCT, though, it can not entirely replace traditional karyotype analysis and gene detection by RT-PCR." @default.
- W2054248997 created "2016-06-24" @default.
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- W2054248997 date "2002-03-01" @default.
- W2054248997 modified "2023-09-22" @default.
- W2054248997 title "Application of two-color interphase fish using sex probe in allogeneic stem cell transplantation" @default.
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- W2054248997 doi "https://doi.org/10.1007/s11670-002-0016-5" @default.
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