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• W2054256297 abstract "Descent into sleep is accompanied by disengagement of the conscious brain from the external world. It follows that this process should be associated with reduced neural activity in regions of the brain known to mediate interaction with the environment. We examined blood oxygen dependent (BOLD) signal functional connectivity using conventional seed-based analyses in 3 primary sensory and 3 association networks as normal young adults transitioned from wakefulness to light sleep while lying immobile in the bore of a magnetic resonance imaging scanner. Functional connectivity was maintained in each network throughout all examined states of arousal. Indeed, correlations within the dorsal attention network modestly but significantly increased during light sleep compared to wakefulness. Moreover, our data suggest that neuronally mediated BOLD signal variance generally increases in light sleep. These results do not support the view that ongoing BOLD fluctuations primarily reflect unconstrained cognition. Rather, accumulating evidence supports the hypothesis that spontaneous BOLD fluctuations reflect processes that maintain the integrity of functional systems in the brain." @default.
• W2054256297 created "2016-06-24" @default.
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• W2054256297 date "2009-03-17" @default.
• W2054256297 modified "2023-10-18" @default.
• W2054256297 title "Cortical network functional connectivity in the descent to sleep" @default.
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• W2054256297 doi "https://doi.org/10.1073/pnas.0900924106" @default.
• W2054256297 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2657465" @default.
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