Matches in SemOpenAlex for { <https://semopenalex.org/work/W2054278011> ?p ?o ?g. }
- W2054278011 endingPage "113" @default.
- W2054278011 startingPage "103" @default.
- W2054278011 abstract "Dopamine secreted from hypophysial hypothalamic neurons is a principal inhibitory regulator of pituitary hormone secretion. Mice with a disrupted D2 dopamine receptor gene had chronic hyperprolactinemia and developed anterior lobe lactotroph hyperplasia without evidence of adenomatous transformation. Unexpectedly, the mutant mice had no hyperplasia of the intermediate lobe melanotrophs. Aged female D2 receptor -/- mice developed uterine adenomyosis in response to prolonged prolactin exposure. These data reveal a critical role of hypothalamic dopamine in controlling pituitary growth and support a multistep mechanism for the induction and perpetuation of lactotroph hyperplasia, involving the lack of dopamine signaling, a low androgen/estrogen ratio, and a final autocrine or paracrine feed-forward stimulation of mitogenesis, probably by prolactin itself." @default.
- W2054278011 created "2016-06-24" @default.
- W2054278011 creator A5005303316 @default.
- W2054278011 creator A5005659657 @default.
- W2054278011 creator A5010962738 @default.
- W2054278011 creator A5012299131 @default.
- W2054278011 creator A5019551454 @default.
- W2054278011 creator A5043828184 @default.
- W2054278011 creator A5044829441 @default.
- W2054278011 creator A5068105950 @default.
- W2054278011 creator A5089173466 @default.
- W2054278011 creator A5090794174 @default.
- W2054278011 creator A5041194223 @default.
- W2054278011 date "1997-07-01" @default.
- W2054278011 modified "2023-10-14" @default.
- W2054278011 title "Pituitary Lactotroph Hyperplasia and Chronic Hyperprolactinemia in Dopamine D2 Receptor-Deficient Mice" @default.
- W2054278011 cites W1488950205 @default.
- W2054278011 cites W1511999259 @default.
- W2054278011 cites W1519825607 @default.
- W2054278011 cites W1539476094 @default.
- W2054278011 cites W1671798294 @default.
- W2054278011 cites W1827831640 @default.
- W2054278011 cites W1966447189 @default.
- W2054278011 cites W1974577580 @default.
- W2054278011 cites W1978850926 @default.
- W2054278011 cites W1988868183 @default.
- W2054278011 cites W1992450113 @default.
- W2054278011 cites W2000151982 @default.
- W2054278011 cites W2004306126 @default.
- W2054278011 cites W2014814706 @default.
- W2054278011 cites W2015597679 @default.
- W2054278011 cites W2016594241 @default.
- W2054278011 cites W2020439478 @default.
- W2054278011 cites W2022151784 @default.
- W2054278011 cites W2029026802 @default.
- W2054278011 cites W2035631751 @default.
- W2054278011 cites W2038370141 @default.
- W2054278011 cites W2040426767 @default.
- W2054278011 cites W2043975218 @default.
- W2054278011 cites W2046555971 @default.
- W2054278011 cites W2047513027 @default.
- W2054278011 cites W2053546036 @default.
- W2054278011 cites W2055144184 @default.
- W2054278011 cites W2057921067 @default.
- W2054278011 cites W2059319460 @default.
- W2054278011 cites W2074558513 @default.
- W2054278011 cites W2086337886 @default.
- W2054278011 cites W2102541501 @default.
- W2054278011 cites W2116711648 @default.
- W2054278011 cites W2118201227 @default.
- W2054278011 cites W2147028876 @default.
- W2054278011 cites W2147666122 @default.
- W2054278011 cites W2151441337 @default.
- W2054278011 cites W2151477904 @default.
- W2054278011 cites W2171666999 @default.
- W2054278011 cites W2333419694 @default.
- W2054278011 cites W4231195547 @default.
- W2054278011 cites W4254043067 @default.
- W2054278011 cites W8693286 @default.
- W2054278011 doi "https://doi.org/10.1016/s0896-6273(00)80351-7" @default.
- W2054278011 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9247267" @default.
- W2054278011 hasPublicationYear "1997" @default.
- W2054278011 type Work @default.
- W2054278011 sameAs 2054278011 @default.
- W2054278011 citedByCount "395" @default.
- W2054278011 countsByYear W20542780112012 @default.
- W2054278011 countsByYear W20542780112013 @default.
- W2054278011 countsByYear W20542780112014 @default.
- W2054278011 countsByYear W20542780112015 @default.
- W2054278011 countsByYear W20542780112016 @default.
- W2054278011 countsByYear W20542780112017 @default.
- W2054278011 countsByYear W20542780112018 @default.
- W2054278011 countsByYear W20542780112019 @default.
- W2054278011 countsByYear W20542780112020 @default.
- W2054278011 countsByYear W20542780112021 @default.
- W2054278011 countsByYear W20542780112022 @default.
- W2054278011 countsByYear W20542780112023 @default.
- W2054278011 crossrefType "journal-article" @default.
- W2054278011 hasAuthorship W2054278011A5005303316 @default.
- W2054278011 hasAuthorship W2054278011A5005659657 @default.
- W2054278011 hasAuthorship W2054278011A5010962738 @default.
- W2054278011 hasAuthorship W2054278011A5012299131 @default.
- W2054278011 hasAuthorship W2054278011A5019551454 @default.
- W2054278011 hasAuthorship W2054278011A5041194223 @default.
- W2054278011 hasAuthorship W2054278011A5043828184 @default.
- W2054278011 hasAuthorship W2054278011A5044829441 @default.
- W2054278011 hasAuthorship W2054278011A5068105950 @default.
- W2054278011 hasAuthorship W2054278011A5089173466 @default.
- W2054278011 hasAuthorship W2054278011A5090794174 @default.
- W2054278011 hasBestOaLocation W20542780111 @default.
- W2054278011 hasConcept C120069818 @default.
- W2054278011 hasConcept C126322002 @default.
- W2054278011 hasConcept C128240485 @default.
- W2054278011 hasConcept C134018914 @default.
- W2054278011 hasConcept C170493617 @default.
- W2054278011 hasConcept C2777658017 @default.
- W2054278011 hasConcept C2778918492 @default.
- W2054278011 hasConcept C2779064019 @default.