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- W2054291341 abstract "We sought to estimate mean costs of chemotherapy treatment for recurrent ovarian cancer with or without use of a chemoresponse assay.We estimated mean costs for 3 groups: (1) assay assisted: 75 women who received oncologist's choice of chemotherapy following chemoresponse testing (65% adherence to test results), (2) assay adherent: modeled group assuming 100% adherence to assay results, and (3) empiric: modeled from market share data on most frequently utilized chemotherapy regimens. Cost estimates were based on commercial claims database reimbursements.The most common chemotherapy regimens used were topotecan, doxorubicin, and carboplatin/paclitaxel. Mean chemotherapy costs for 6 cycles were $48,758 (empiric), $33,187 (assay assisted), and $23,986 (assay adherent). The cost savings related to the assay were associated with a shift from higher- to lower-cost chemotherapy regimens and lower use of supportive drugs such as hematopoiesis-stimulating agents.Assay-assisted chemotherapy for recurrent ovarian cancer may result in reduced costs compared to empiric therapy." @default.
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- W2054291341 date "2010-08-01" @default.
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- W2054291341 title "Impact of a chemoresponse assay on treatment costs for recurrent ovarian cancer" @default.
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- W2054291341 doi "https://doi.org/10.1016/j.ajog.2010.02.054" @default.
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