Matches in SemOpenAlex for { <https://semopenalex.org/work/W2054299085> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2054299085 endingPage "9" @default.
- W2054299085 startingPage "411" @default.
- W2054299085 abstract "The present study tested a hypothesis, whether plant-derived genistein influences the secretion of growth hormone (GH) in ewes, acting directly within the central nervous system (CNS). Starting six weeks after ovariectomy, ewes were infused intracerebroventricularly with genistein (n = 5) or 17beta-estradiol (n = 5), both in a total dose of 40 microg/400 microl/4 h, or with a vehicle (control, n = 5). All infusions were performed from 10:00 AM to 2:00 PM and blood samples were collected from 8:00 AM to 8:00 PM at 10-min intervals. Five genistein- and three vehicle-infused ewes were slaughtered the following morning. The plasma GH concentration was assayed by the radioimmunoassay method, and immunoreactivity of GH in the adenohypophysis was determined by immunohistochemistry. In genistein-infused ewes, mean plasma GH concentration was significantly higher during the whole period of infusion than the concomitant concentration in vehicle-infused ewes. However, examining data within group, GH secretion rose gradually, reaching a significant value during the second phase of genistein infusion. In 17beta-estradiol-infused animals, a significant increase in GH concentration was noted during the first two hours of the infusion, in comparison with vehicle-infused and also in comparison with genistein-infused ewes. Although a gradual increase in basic GH secretion continued in all treated groups during the afternoon and evening, mean plasma GH concentrations in genistein- and 17beta-estradiol-infused ewes were still significantly higher than in the vehicle-infused. The percentage of GH-positive cells in the adenohypophysis and the density of immunoreactive material in these cells decreased significantly in genistein-infused ewes, compared to the control, indicating diminished hormone storage. In conclusion, genistein as 17beta-estradiol, is an effective stimulator of GH secretion in ewes and may exert its effect at the level of the CNS." @default.
- W2054299085 created "2016-06-24" @default.
- W2054299085 creator A5016354319 @default.
- W2054299085 creator A5045506634 @default.
- W2054299085 creator A5050860051 @default.
- W2054299085 creator A5074438452 @default.
- W2054299085 date "2007-01-01" @default.
- W2054299085 modified "2023-09-27" @default.
- W2054299085 title "Central estrogen-like effect of genistein on growth hormone secretion in the ewe." @default.
- W2054299085 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18320719" @default.
- W2054299085 hasPublicationYear "2007" @default.
- W2054299085 type Work @default.
- W2054299085 sameAs 2054299085 @default.
- W2054299085 citedByCount "6" @default.
- W2054299085 countsByYear W20542990852013 @default.
- W2054299085 countsByYear W20542990852014 @default.
- W2054299085 countsByYear W20542990852016 @default.
- W2054299085 countsByYear W20542990852018 @default.
- W2054299085 countsByYear W20542990852019 @default.
- W2054299085 crossrefType "journal-article" @default.
- W2054299085 hasAuthorship W2054299085A5016354319 @default.
- W2054299085 hasAuthorship W2054299085A5045506634 @default.
- W2054299085 hasAuthorship W2054299085A5050860051 @default.
- W2054299085 hasAuthorship W2054299085A5074438452 @default.
- W2054299085 hasConcept C121332964 @default.
- W2054299085 hasConcept C126322002 @default.
- W2054299085 hasConcept C1276947 @default.
- W2054299085 hasConcept C134018914 @default.
- W2054299085 hasConcept C176685330 @default.
- W2054299085 hasConcept C185592680 @default.
- W2054299085 hasConcept C19720800 @default.
- W2054299085 hasConcept C2776476923 @default.
- W2054299085 hasConcept C2777164284 @default.
- W2054299085 hasConcept C2778298627 @default.
- W2054299085 hasConcept C2779064019 @default.
- W2054299085 hasConcept C49039625 @default.
- W2054299085 hasConcept C71315377 @default.
- W2054299085 hasConcept C71924100 @default.
- W2054299085 hasConcept C86803240 @default.
- W2054299085 hasConceptScore W2054299085C121332964 @default.
- W2054299085 hasConceptScore W2054299085C126322002 @default.
- W2054299085 hasConceptScore W2054299085C1276947 @default.
- W2054299085 hasConceptScore W2054299085C134018914 @default.
- W2054299085 hasConceptScore W2054299085C176685330 @default.
- W2054299085 hasConceptScore W2054299085C185592680 @default.
- W2054299085 hasConceptScore W2054299085C19720800 @default.
- W2054299085 hasConceptScore W2054299085C2776476923 @default.
- W2054299085 hasConceptScore W2054299085C2777164284 @default.
- W2054299085 hasConceptScore W2054299085C2778298627 @default.
- W2054299085 hasConceptScore W2054299085C2779064019 @default.
- W2054299085 hasConceptScore W2054299085C49039625 @default.
- W2054299085 hasConceptScore W2054299085C71315377 @default.
- W2054299085 hasConceptScore W2054299085C71924100 @default.
- W2054299085 hasConceptScore W2054299085C86803240 @default.
- W2054299085 hasIssue "4" @default.
- W2054299085 hasLocation W20542990851 @default.
- W2054299085 hasOpenAccess W2054299085 @default.
- W2054299085 hasPrimaryLocation W20542990851 @default.
- W2054299085 hasRelatedWork W1977511523 @default.
- W2054299085 hasRelatedWork W1981845717 @default.
- W2054299085 hasRelatedWork W1987081056 @default.
- W2054299085 hasRelatedWork W1988561718 @default.
- W2054299085 hasRelatedWork W2007140444 @default.
- W2054299085 hasRelatedWork W2008555979 @default.
- W2054299085 hasRelatedWork W2013829548 @default.
- W2054299085 hasRelatedWork W2049058807 @default.
- W2054299085 hasRelatedWork W2049338599 @default.
- W2054299085 hasRelatedWork W2053734821 @default.
- W2054299085 hasRelatedWork W2068072424 @default.
- W2054299085 hasRelatedWork W2069688139 @default.
- W2054299085 hasRelatedWork W2074371312 @default.
- W2054299085 hasRelatedWork W2076484554 @default.
- W2054299085 hasRelatedWork W2110982022 @default.
- W2054299085 hasRelatedWork W2127996981 @default.
- W2054299085 hasRelatedWork W2411406810 @default.
- W2054299085 hasRelatedWork W2415011507 @default.
- W2054299085 hasRelatedWork W2427964316 @default.
- W2054299085 hasRelatedWork W2184175181 @default.
- W2054299085 hasVolume "67" @default.
- W2054299085 isParatext "false" @default.
- W2054299085 isRetracted "false" @default.
- W2054299085 magId "2054299085" @default.
- W2054299085 workType "article" @default.