FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2054339670> ?p ?o ?g. }

• W2054339670 abstract "Abstract We describe here the structure–property–process relationship of two sets of chitosan‐based scaffolds as potential materials for hard tissue bioengineering applications. The first set of scaffolds was designed to study the effect of degree of deacetylation (%DD) of chitosan at 85 and 95% DD with identical molecular weight. The second set of scaffolds were synthesized to enhance the bioactivity and mechanical properties of 95% DD chitosan scaffold by the addition of 1, 3, and 5 wt% nanohydroxyapatite (nHA). Both sets of scaffolds were processed using freezing and lyophilization and their in vitro biological response was examined using pre‐osteoblast (MC 3T3‐E1) cells. The pure chitosan and chitosan–nHA nanocomposite scaffolds were characterized by a three‐dimensional porous structure with pore size in the range of (≈50–120 µm), irrespective of %DD and nHA content. The compression modulus of hydrated 95% DD chitosan scaffolds increased from 6.0 kPa in pure chitosan to 9.2 kPa in chitosan‐5 wt% nHA . The water uptake ability of 95% DD chitosan scaffolds was lower than 85% DD chitosan scaffolds, and decreased with the addition of nHA. On the other hand the water retention ability of 95% DD chitosan scaffolds was greater than 85% DD chitosan scaffolds but did not increase much with the addition of nHA. Chitosan degrades mainly by lysozyme present in physiological fluid. After 28 days of in vitro biodegradation test with physiological fluid, the 95% DD chitosan exhibited slightly lower degradation rate as compared to 85% DD and the degradation decreased with increase in nHA content in chitosan scaffold. Pre‐osteoblasts (MC3T3‐E1) grown on nHA scaffolds showed improved cell attachment, more proliferation, and a more extended cellular morphology. In vitro experimental observations suggest chitosan–nHA nanocomposite scaffolds as potential biomaterials for hard tissue bioengineering (bone regeneration) or as a template for cell attachment and proliferation in the repair of osseous and chondral defects." @default.
• W2054339670 created "2016-06-24" @default.
• W2054339670 creator A5002519672 @default.
• W2054339670 creator A5032365679 @default.
• W2054339670 creator A5068543696 @default.
• W2054339670 creator A5069877034 @default.
• W2054339670 creator A5087832932 @default.
• W2054339670 date "2011-01-17" @default.
• W2054339670 modified "2023-10-05" @default.
• W2054339670 title "Structure-Process-Property Relationship of Biomimetic Chitosan-Based Nanocomposite Scaffolds for Tissue Engineering: Biological, Physico-Chemical, and Mechanical Functions" @default.
• W2054339670 cites W1883215304 @default.
• W2054339670 cites W1966766783 @default.
• W2054339670 cites W1966784873 @default.
• W2054339670 cites W1976913986 @default.
• W2054339670 cites W1982839241 @default.
• W2054339670 cites W1984734563 @default.
• W2054339670 cites W1987190449 @default.
• W2054339670 cites W1996513265 @default.
• W2054339670 cites W1998002551 @default.
• W2054339670 cites W2005749200 @default.
• W2054339670 cites W2012201158 @default.
• W2054339670 cites W2012293496 @default.
• W2054339670 cites W2019167552 @default.
• W2054339670 cites W2033629718 @default.
• W2054339670 cites W2034479167 @default.
• W2054339670 cites W2034656256 @default.
• W2054339670 cites W2034829127 @default.
• W2054339670 cites W2040272006 @default.
• W2054339670 cites W2048381378 @default.
• W2054339670 cites W2050154892 @default.
• W2054339670 cites W2055476008 @default.
• W2054339670 cites W2056163086 @default.
• W2054339670 cites W2056375233 @default.
• W2054339670 cites W2064894420 @default.
• W2054339670 cites W2067719770 @default.
• W2054339670 cites W2073822753 @default.
• W2054339670 cites W2074865082 @default.
• W2054339670 cites W2076276686 @default.
• W2054339670 cites W2076478919 @default.
• W2054339670 cites W2078671776 @default.
• W2054339670 cites W2087783018 @default.
• W2054339670 cites W2090836893 @default.
• W2054339670 cites W2093489000 @default.
• W2054339670 cites W2096420560 @default.
• W2054339670 cites W2114260548 @default.
• W2054339670 cites W2120791646 @default.
• W2054339670 cites W2121331825 @default.
• W2054339670 cites W2139457077 @default.
• W2054339670 cites W2152233267 @default.
• W2054339670 cites W2159356254 @default.
• W2054339670 cites W4211147424 @default.
• W2054339670 doi "https://doi.org/10.1002/adem.201080094" @default.
• W2054339670 hasPublicationYear "2011" @default.
• W2054339670 type Work @default.
• W2054339670 sameAs 2054339670 @default.
• W2054339670 citedByCount "54" @default.
• W2054339670 countsByYear W20543396702012 @default.
• W2054339670 countsByYear W20543396702013 @default.
• W2054339670 countsByYear W20543396702014 @default.
• W2054339670 countsByYear W20543396702015 @default.
• W2054339670 countsByYear W20543396702016 @default.
• W2054339670 countsByYear W20543396702017 @default.
• W2054339670 countsByYear W20543396702018 @default.
• W2054339670 countsByYear W20543396702019 @default.
• W2054339670 countsByYear W20543396702020 @default.
• W2054339670 countsByYear W20543396702021 @default.
• W2054339670 countsByYear W20543396702022 @default.
• W2054339670 countsByYear W20543396702023 @default.
• W2054339670 crossrefType "journal-article" @default.
• W2054339670 hasAuthorship W2054339670A5002519672 @default.
• W2054339670 hasAuthorship W2054339670A5032365679 @default.
• W2054339670 hasAuthorship W2054339670A5068543696 @default.
• W2054339670 hasAuthorship W2054339670A5069877034 @default.
• W2054339670 hasAuthorship W2054339670A5087832932 @default.
• W2054339670 hasConcept C127413603 @default.
• W2054339670 hasConcept C136229726 @default.
• W2054339670 hasConcept C157021035 @default.
• W2054339670 hasConcept C159985019 @default.
• W2054339670 hasConcept C178790620 @default.
• W2054339670 hasConcept C185592680 @default.
• W2054339670 hasConcept C192562407 @default.
• W2054339670 hasConcept C2779732960 @default.
• W2054339670 hasConcept C42360764 @default.
• W2054339670 hasConcept C49892992 @default.
• W2054339670 hasConcept C71924100 @default.
• W2054339670 hasConcept C92880739 @default.
• W2054339670 hasConceptScore W2054339670C127413603 @default.
• W2054339670 hasConceptScore W2054339670C136229726 @default.
• W2054339670 hasConceptScore W2054339670C157021035 @default.
• W2054339670 hasConceptScore W2054339670C159985019 @default.
• W2054339670 hasConceptScore W2054339670C178790620 @default.
• W2054339670 hasConceptScore W2054339670C185592680 @default.
• W2054339670 hasConceptScore W2054339670C192562407 @default.
• W2054339670 hasConceptScore W2054339670C2779732960 @default.
• W2054339670 hasConceptScore W2054339670C42360764 @default.
• W2054339670 hasConceptScore W2054339670C49892992 @default.
• W2054339670 hasConceptScore W2054339670C71924100 @default.
• W2054339670 hasConceptScore W2054339670C92880739 @default.
• W2054339670 hasIssue "3" @default.
• W2054339670 hasLocation W20543396701 @default.

• next