FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2054357130> ?p ?o ?g. }

• W2054357130 endingPage "12" @default.
• W2054357130 startingPage "6" @default.
• W2054357130 abstract "Previous work from this laboratory has demonstrated that prior exposure of peripheral blood monocytes (PBM) to aggregated beta-amyloid peptide (Aβ), the major protein comprising the amyloid plaques characteristically present in the brain of Alzheimer disease (AD)-afflicted individuals, activates these cells to a neurotoxic state when co-cultured with brain tissue. In this report we extend these findings to further show that such Aβ-induced PBM neurotoxicity can be inhibited by three differentially-acting antiinflammatory drugs, indomethacin, dexamethasone, and colchicine, which are typically used clinically to treat peripheral inflammatory disease. In addition, evidence is presented that these toxic effects are initiated, in large part, by soluble factors released from Aβ-stimulated PBM. Our results suggest a rationale for antiinflammatory therapy in the treatment of AD." @default.
• W2054357130 created "2016-06-24" @default.
• W2054357130 creator A5054045746 @default.
• W2054357130 creator A5068883382 @default.
• W2054357130 creator A5091603636 @default.
• W2054357130 date "1997-12-01" @default.
• W2054357130 modified "2023-10-11" @default.
• W2054357130 title "Suppression of Aβ-induced monocyte neurotoxicity by antiinflammatory compounds" @default.
• W2054357130 cites W1500372714 @default.
• W2054357130 cites W1582483157 @default.
• W2054357130 cites W1614954929 @default.
• W2054357130 cites W1967674023 @default.
• W2054357130 cites W1969257616 @default.
• W2054357130 cites W1973238388 @default.
• W2054357130 cites W1976080589 @default.
• W2054357130 cites W1976647609 @default.
• W2054357130 cites W1984461707 @default.
• W2054357130 cites W1988507091 @default.
• W2054357130 cites W1991763618 @default.
• W2054357130 cites W1991814736 @default.
• W2054357130 cites W2031925670 @default.
• W2054357130 cites W2035113730 @default.
• W2054357130 cites W2038031810 @default.
• W2054357130 cites W2038611817 @default.
• W2054357130 cites W2045213688 @default.
• W2054357130 cites W2045560271 @default.
• W2054357130 cites W2046454316 @default.
• W2054357130 cites W2047313830 @default.
• W2054357130 cites W2068183846 @default.
• W2054357130 cites W2069039065 @default.
• W2054357130 cites W2074274825 @default.
• W2054357130 cites W2074443913 @default.
• W2054357130 cites W2075882827 @default.
• W2054357130 cites W2076162707 @default.
• W2054357130 cites W2078675846 @default.
• W2054357130 cites W2079026827 @default.
• W2054357130 cites W2080411212 @default.
• W2054357130 cites W2085138530 @default.
• W2054357130 cites W2086010070 @default.
• W2054357130 cites W2090930997 @default.
• W2054357130 cites W2092411904 @default.
• W2054357130 cites W2116605894 @default.
• W2054357130 cites W2144192610 @default.
• W2054357130 cites W2145803099 @default.
• W2054357130 cites W2891254421 @default.
• W2054357130 cites W38748857 @default.
• W2054357130 cites W4211261134 @default.
• W2054357130 doi "https://doi.org/10.1016/s0165-5728(97)00128-8" @default.
• W2054357130 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9413254" @default.
• W2054357130 hasPublicationYear "1997" @default.
• W2054357130 type Work @default.
• W2054357130 sameAs 2054357130 @default.
• W2054357130 citedByCount "29" @default.
• W2054357130 countsByYear W20543571302014 @default.
• W2054357130 countsByYear W20543571302015 @default.
• W2054357130 countsByYear W20543571302022 @default.
• W2054357130 crossrefType "journal-article" @default.
• W2054357130 hasAuthorship W2054357130A5054045746 @default.
• W2054357130 hasAuthorship W2054357130A5068883382 @default.
• W2054357130 hasAuthorship W2054357130A5091603636 @default.
• W2054357130 hasConcept C126322002 @default.
• W2054357130 hasConcept C142724271 @default.
• W2054357130 hasConcept C203014093 @default.
• W2054357130 hasConcept C2776636253 @default.
• W2054357130 hasConcept C2776914184 @default.
• W2054357130 hasConcept C2777633098 @default.
• W2054357130 hasConcept C2779134260 @default.
• W2054357130 hasConcept C2779491297 @default.
• W2054357130 hasConcept C2780401358 @default.
• W2054357130 hasConcept C2781184567 @default.
• W2054357130 hasConcept C29730261 @default.
• W2054357130 hasConcept C46762472 @default.
• W2054357130 hasConcept C71924100 @default.
• W2054357130 hasConcept C98274493 @default.
• W2054357130 hasConceptScore W2054357130C126322002 @default.
• W2054357130 hasConceptScore W2054357130C142724271 @default.
• W2054357130 hasConceptScore W2054357130C203014093 @default.
• W2054357130 hasConceptScore W2054357130C2776636253 @default.
• W2054357130 hasConceptScore W2054357130C2776914184 @default.
• W2054357130 hasConceptScore W2054357130C2777633098 @default.
• W2054357130 hasConceptScore W2054357130C2779134260 @default.
• W2054357130 hasConceptScore W2054357130C2779491297 @default.
• W2054357130 hasConceptScore W2054357130C2780401358 @default.
• W2054357130 hasConceptScore W2054357130C2781184567 @default.
• W2054357130 hasConceptScore W2054357130C29730261 @default.
• W2054357130 hasConceptScore W2054357130C46762472 @default.
• W2054357130 hasConceptScore W2054357130C71924100 @default.
• W2054357130 hasConceptScore W2054357130C98274493 @default.
• W2054357130 hasIssue "1-2" @default.
• W2054357130 hasLocation W20543571301 @default.
• W2054357130 hasLocation W20543571302 @default.
• W2054357130 hasOpenAccess W2054357130 @default.
• W2054357130 hasPrimaryLocation W20543571301 @default.
• W2054357130 hasRelatedWork W1980147610 @default.
• W2054357130 hasRelatedWork W2027598096 @default.
• W2054357130 hasRelatedWork W2083932001 @default.
• W2054357130 hasRelatedWork W2088338328 @default.
• W2054357130 hasRelatedWork W2124704280 @default.

• next