FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2054404077> ?p ?o ?g. }

• W2054404077 endingPage "47" @default.
• W2054404077 startingPage "35" @default.
• W2054404077 abstract "The influence of single oral dosages of carbamazepine (CBZ), valproic acid, vigabatrin (VGB), lamotrigine (LTG), gabapentin (GBP), and losigamone (LSG) on visual perception was investigated in ten healthy volunteers according to a double-blind, placebo-controlled, cross-over study design. The test battery comprised visual acuity, the Lanthony-D-15-désaturé colour perception test, increment, postadaptation and transient tritanopia threshold measurements, perception threshold assessment for monochromatic and chromatic gaussian dots, monochromatic gratings and gratings of differing spatial frequency, and critical flicker fusion tests with various stimuli. The only consistent and partly significant effects were seen after VGB and GBP. After VGB, increment, postadaptation and transient tritanopia thresholds and the critical flicker fusion increased, whereas GBP led to a somewhat converse profile. The other tests were not influenced consistently by any antiepileptic drug (AED). We conclude that: (i) gamma-amino-butyric acid-(GABA)-related properties as under the prototype drug VGB result in specific alterations of the transient tritanopia phenomenon which is consistent with the physiological hypothesis for this retinal paradigm based on extracellular recordings in primates. The possible mechanisms why VGB improved critical flicker fusion as the only AED in this trial are discussed. The profile of GBP indicates a unique mechanism of action. We have not observed specific influences on visual perception under AEDs which act mainly via alterations of ion membrane conductance. The transient tritanopia and flicker fusion paradigms we used appear to be promising to investigate antiepileptic drugs with hitherto unknown modes of actions in human noninvasively." @default.
• W2054404077 created "2016-06-24" @default.
• W2054404077 creator A5049348155 @default.
• W2054404077 creator A5052195171 @default.
• W2054404077 creator A5084472327 @default.
• W2054404077 date "1997-12-01" @default.
• W2054404077 modified "2023-10-10" @default.
• W2054404077 title "The influence of established and new antiepileptic drugs on visual perception. 1. A placebo-controlled, double-blind, single-dose study in healthy volunteers" @default.
• W2054404077 cites W1206115187 @default.
• W2054404077 cites W1817006636 @default.
• W2054404077 cites W1966474984 @default.
• W2054404077 cites W1967586886 @default.
• W2054404077 cites W1969032718 @default.
• W2054404077 cites W1972973827 @default.
• W2054404077 cites W1977300182 @default.
• W2054404077 cites W1981369761 @default.
• W2054404077 cites W1984486611 @default.
• W2054404077 cites W1984486655 @default.
• W2054404077 cites W1996273315 @default.
• W2054404077 cites W1997290677 @default.
• W2054404077 cites W1998356121 @default.
• W2054404077 cites W2004043769 @default.
• W2054404077 cites W2004511526 @default.
• W2054404077 cites W2006059803 @default.
• W2054404077 cites W2008276527 @default.
• W2054404077 cites W2011525452 @default.
• W2054404077 cites W2015575104 @default.
• W2054404077 cites W2018671604 @default.
• W2054404077 cites W2022709815 @default.
• W2054404077 cites W2034845337 @default.
• W2054404077 cites W2036294580 @default.
• W2054404077 cites W2037856045 @default.
• W2054404077 cites W2043057314 @default.
• W2054404077 cites W2044079792 @default.
• W2054404077 cites W2046966869 @default.
• W2054404077 cites W2047058791 @default.
• W2054404077 cites W2047744286 @default.
• W2054404077 cites W2049512910 @default.
• W2054404077 cites W2076683196 @default.
• W2054404077 cites W2081758626 @default.
• W2054404077 cites W2082270842 @default.
• W2054404077 cites W2084778535 @default.
• W2054404077 cites W2086963093 @default.
• W2054404077 cites W2088937042 @default.
• W2054404077 cites W2089240430 @default.
• W2054404077 cites W2090444332 @default.
• W2054404077 cites W2090976027 @default.
• W2054404077 cites W2097983819 @default.
• W2054404077 cites W2099027764 @default.
• W2054404077 cites W2100431066 @default.
• W2054404077 cites W2100887132 @default.
• W2054404077 cites W2108660693 @default.
• W2054404077 cites W2119093004 @default.
• W2054404077 cites W2133740066 @default.
• W2054404077 cites W2138533817 @default.
• W2054404077 cites W2142965243 @default.
• W2054404077 cites W27254563 @default.
• W2054404077 doi "https://doi.org/10.1016/s0920-1211(97)00060-0" @default.
• W2054404077 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9416458" @default.
• W2054404077 hasPublicationYear "1997" @default.
• W2054404077 type Work @default.
• W2054404077 sameAs 2054404077 @default.
• W2054404077 citedByCount "34" @default.
• W2054404077 countsByYear W20544040772014 @default.
• W2054404077 countsByYear W20544040772016 @default.
• W2054404077 countsByYear W20544040772019 @default.
• W2054404077 countsByYear W20544040772021 @default.
• W2054404077 countsByYear W20544040772022 @default.
• W2054404077 crossrefType "journal-article" @default.
• W2054404077 hasAuthorship W2054404077A5049348155 @default.
• W2054404077 hasAuthorship W2054404077A5052195171 @default.
• W2054404077 hasAuthorship W2054404077A5084472327 @default.
• W2054404077 hasConcept C111919701 @default.
• W2054404077 hasConcept C142724271 @default.
• W2054404077 hasConcept C152484397 @default.
• W2054404077 hasConcept C15744967 @default.
• W2054404077 hasConcept C169760540 @default.
• W2054404077 hasConcept C19743564 @default.
• W2054404077 hasConcept C204787440 @default.
• W2054404077 hasConcept C2775858608 @default.
• W2054404077 hasConcept C2776608144 @default.
• W2054404077 hasConcept C2777172819 @default.
• W2054404077 hasConcept C2778186239 @default.
• W2054404077 hasConcept C2778802184 @default.
• W2054404077 hasConcept C2779253243 @default.
• W2054404077 hasConcept C2780837902 @default.
• W2054404077 hasConcept C41008148 @default.
• W2054404077 hasConcept C42219234 @default.
• W2054404077 hasConcept C548259974 @default.
• W2054404077 hasConcept C71924100 @default.
• W2054404077 hasConcept C98274493 @default.
• W2054404077 hasConceptScore W2054404077C111919701 @default.
• W2054404077 hasConceptScore W2054404077C142724271 @default.
• W2054404077 hasConceptScore W2054404077C152484397 @default.
• W2054404077 hasConceptScore W2054404077C15744967 @default.
• W2054404077 hasConceptScore W2054404077C169760540 @default.
• W2054404077 hasConceptScore W2054404077C19743564 @default.
• W2054404077 hasConceptScore W2054404077C204787440 @default.

• next