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• W2054418618 abstract "A rationally designed Pt(IV) anticancer compound is described, employing the novel concept of tethering an inhibitor of glutathione-S-transferase, an enzyme associated with Pt-based drug-resistance, to cisplatin. Its enzyme inhibition activity, investigated using spectrophotometric and mass spectrometry-based techniques, and cytotoxic profile in resistant cancer cells are described." @default.
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• W2054418618 date "2005-01-13" @default.
• W2054418618 modified "2023-10-02" @default.
• W2054418618 title "Rational Design of Platinum(IV) Compounds to Overcome Glutathione-S-Transferase Mediated Drug Resistance" @default.
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• W2054418618 doi "https://doi.org/10.1021/ja0432618" @default.
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