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- W2054443145 abstract "A dose dependent increase in rat hepatic microsomal demethylase activities associated with an increase in relative liver weight was found after repeated i.p. injections of piperonyl butoxide. Type I substrates were used (see Materials and Methods). The degree of induction was similar to that seen after treatment with DDT. An increase in demethylase activities was not found in preparations from brain, kidney, lung and small intestine. Inhibition following a single injection of piperonyl butoxide could not be demonstrated. The apparent discrepancy of this result with the known inhibitory effect of piperonyl butoxide on microsomal preparations from insects, and experiments reported with mice, is discussed." @default.
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- W2054443145 date "1972-08-01" @default.
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- W2054443145 title "The inductive effect of piperonyl butoxide on microsomal demethylase activity" @default.
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- W2054443145 doi "https://doi.org/10.1016/0048-9697(72)90006-x" @default.
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