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• W2054463910 abstract "The objective of this research was to determine the true superoxide (O2−) scavenging activity of antioxidants in a sample containing xanthine oxidase (XOD) inhibitor. A previous method involving electron spin resonance (ESR) spin-trapping has generally used 5,5-dimethyl-1-pyrroline 1-oxide (DMPO) as a spin trap and the O2− generation system of hypoxanthine (HPX)-xanthine oxidase (XOD). However, this method has a problem in that the ESR signal intensity of the DMPO spin adduct of O2− (DMPO-OOH) is decreased not only by the reaction of a sample with O2−, but also by the inhibition of XOD. Therefore, the ESR spin-trapping method combined with the SOD addition method was developed as a new experimental technique in this study. The results indicate that the O2− scavenging activity of a sample containing allopurinol as an XOD inhibitor could be determined by using this method." @default.
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• W2054463910 date "2000-10-01" @default.
• W2054463910 modified "2023-10-14" @default.
• W2054463910 title "Determination of Superoxide Scavenging Activity of a Sample Containing Xanthine Oxidase Inhibitor by ESR Spin Trapping" @default.
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• W2054463910 doi "https://doi.org/10.2116/analsci.16.1029" @default.
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